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Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system.
Gao Y, Wang Y, Chauss D, Villarino AV, Link VM, Nagashima H, Spinner CA, Koparde VN, Bouladoux N, Abers MS, Break TJ, Chopp LB, Park JH, Zhu J, Wiest DL, Leonard WJ, Lionakis MS, O'Shea JJ, Afzali B, Belkaid Y, Lazarevic V. Gao Y, et al. Among authors: break tj. Nat Immunol. 2023 Aug;24(8):1331-1344. doi: 10.1038/s41590-023-01553-7. Epub 2023 Jul 13. Nat Immunol. 2023. PMID: 37443284 Free PMC article.
Infections in the monogenic autoimmune syndrome APECED.
Oikonomou V, Break TJ, Gaffen SL, Moutsopoulos NM, Lionakis MS. Oikonomou V, et al. Among authors: break tj. Curr Opin Immunol. 2021 Oct;72:286-297. doi: 10.1016/j.coi.2021.07.011. Epub 2021 Aug 18. Curr Opin Immunol. 2021. PMID: 34418591 Free PMC article. Review.
Aberrant type 1 immunity drives susceptibility to mucosal fungal infections.
Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D; Genomics and Computational Biology Core; Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. Break TJ, et al. Science. 2021 Jan 15;371(6526):eaay5731. doi: 10.1126/science.aay5731. Science. 2021. PMID: 33446526 Free PMC article.
On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.
Dutzan N, Abusleme L, Bridgeman H, Greenwell-Wild T, Zangerle-Murray T, Fife ME, Bouladoux N, Linley H, Brenchley L, Wemyss K, Calderon G, Hong BY, Break TJ, Bowdish DME, Lionakis MS, Jones SA, Trinchieri G, Diaz PI, Belkaid Y, Konkel JE, Moutsopoulos NM. Dutzan N, et al. Among authors: break tj. Immunity. 2017 Jan 17;46(1):133-147. doi: 10.1016/j.immuni.2016.12.010. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087239 Free PMC article.
Response to Comments on "Aberrant type 1 immunity drives susceptibility to mucosal fungal infections".
Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D; Genomics and Computational Biology Core16; Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. Break TJ, et al. Science. 2021 Sep 17;373(6561):eabi8835. doi: 10.1126/science.abi8835. Epub 2021 Sep 16. Science. 2021. PMID: 34529475 Free PMC article.
Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis.
Aggor FEY, Break TJ, Trevejo-Nuñez G, Whibley N, Coleman BM, Bailey RD, Kaplan DH, Naglik JR, Shan W, Shetty AC, McCracken C, Durum SK, Biswas PS, Bruno VM, Kolls JK, Lionakis MS, Gaffen SL. Aggor FEY, et al. Among authors: break tj. Sci Immunol. 2020 Jun 5;5(48):eaba0570. doi: 10.1126/sciimmunol.aba0570. Sci Immunol. 2020. PMID: 32503875 Free PMC article.
CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.
Swamydas M, Gao JL, Break TJ, Johnson MD, Jaeger M, Rodriguez CA, Lim JK, Green NM, Collar AL, Fischer BG, Lee CC, Perfect JR, Alexander BD, Kullberg BJ, Netea MG, Murphy PM, Lionakis MS. Swamydas M, et al. Among authors: break tj. Sci Transl Med. 2016 Jan 20;8(322):322ra10. doi: 10.1126/scitranslmed.aac7718. Sci Transl Med. 2016. PMID: 26791948 Free PMC article.
23 results