Brazina J - Search Results

1

Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.

Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, Jackson SP, Caldecott KW. Serrano-Benitez A, et al. Among authors: brazina j. EMBO J. 2023 Sep 18;42(18):e113190. doi: 10.15252/embj.2022113190. Epub 2023 Jul 26. EMBO J. 2023. PMID: 37492888 Free PMC article.

2

Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia.

Zagnoli-Vieira G, Brazina J, Van Den Bogaert K, Huybrechts W, Molenaers G, Caldecott KW, Van Esch H. Zagnoli-Vieira G, et al. Among authors: brazina j. Hum Genet. 2023 Sep;142(9):1417-1427. doi: 10.1007/s00439-023-02589-3. Epub 2023 Aug 10. Hum Genet. 2023. PMID: 37558815 Free PMC article.

3

Novel PNKP mutations associated with reduced DNA single-strand break repair and severe microcephaly, seizures, and developmental delay.

Thuresson AC, Brazina J, Akram T, Albrecht J, Dahl N, Soussi Zander C, Caldecott KW. Thuresson AC, et al. Among authors: brazina j. Mol Genet Genomic Med. 2024 Jan;12(1):e2295. doi: 10.1002/mgg3.2295. Epub 2023 Nov 2. Mol Genet Genomic Med. 2024. PMID: 37916443 Free PMC article.

4

APE1-dependent base excision repair of DNA photodimers in human cells.

Gautam A, Fawcett H, Burdova K, Brazina J, Caldecott KW. Gautam A, et al. Among authors: brazina j. Mol Cell. 2023 Oct 19;83(20):3669-3678.e7. doi: 10.1016/j.molcel.2023.09.013. Epub 2023 Oct 9. Mol Cell. 2023. PMID: 37816354 Free article.

5

XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair.

Adamowicz M, Hailstone R, Demin AA, Komulainen E, Hanzlikova H, Brazina J, Gautam A, Wells SE, Caldecott KW. Adamowicz M, et al. Among authors: brazina j. Nat Cell Biol. 2021 Dec;23(12):1287-1298. doi: 10.1038/s41556-021-00792-w. Epub 2021 Nov 22. Nat Cell Biol. 2021. PMID: 34811483 Free PMC article.

6

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.

Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW. Demin AA, et al. Among authors: brazina j. Mol Cell. 2021 Jul 15;81(14):3018-3030.e5. doi: 10.1016/j.molcel.2021.05.009. Epub 2021 Jun 7. Mol Cell. 2021. PMID: 34102106 Free PMC article.

7

Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair.

Hanzlikova H, Prokhorova E, Krejcikova K, Cihlarova Z, Kalasova I, Kubovciak J, Sachova J, Hailstone R, Brazina J, Ghosh S, Cirak S, Gleeson JG, Ahel I, Caldecott KW. Hanzlikova H, et al. Among authors: brazina j. Nat Commun. 2020 Jul 7;11(1):3391. doi: 10.1038/s41467-020-17069-9. Nat Commun. 2020. PMID: 32636369 Free PMC article.

8

Multifunctional adaptor protein Daxx interacts with chromatin-remodelling ATPase Brg1.

Svadlenka J, Brazina J, Hanzlikova H, Cermak L, Andera L. Svadlenka J, et al. Among authors: brazina j. Biochem Biophys Rep. 2015 Dec 30;5:246-252. doi: 10.1016/j.bbrep.2015.12.012. eCollection 2016 Mar. Biochem Biophys Rep. 2015. PMID: 28955830 Free PMC article.

9

Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma.

Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, Prukova D, Vejmelkova D, Jaksa R, Helman K, Vockova P, Lateckova L, Molinsky J, Maswabi BC, Alam M, Kodet R, Pytlik R, Trneny M, Klener P. Klanova M, et al. Among authors: brazina j. Clin Cancer Res. 2016 Mar 1;22(5):1138-49. doi: 10.1158/1078-0432.CCR-15-1191. Epub 2015 Oct 14. Clin Cancer Res. 2016. PMID: 26467384

10

DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.

Brazina J, Svadlenka J, Macurek L, Andera L, Hodny Z, Bartek J, Hanzlikova H. Brazina J, et al. Cell Cycle. 2015;14(3):375-87. doi: 10.4161/15384101.2014.988019. Cell Cycle. 2015. PMID: 25659035 Free PMC article.

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