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Page 1
p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.
Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM. Saiz-Ladera C, et al. Among authors: bravo a. Oncogene. 2014 Sep 11;33(37):4599-4612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14. Oncogene. 2014. PMID: 24121270 Free PMC article.
Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.
Moral M, Segrelles C, Lara MF, Martínez-Cruz AB, Lorz C, Santos M, García-Escudero R, Lu J, Kiguchi K, Buitrago A, Costa C, Saiz C, Rodriguez-Peralto JL, Martinez-Tello FJ, Rodriguez-Pinilla M, Sanchez-Cespedes M, Garín M, Grande T, Bravo A, DiGiovanni J, Paramio JM. Moral M, et al. Among authors: bravo a. Cancer Res. 2009 Feb 1;69(3):1099-108. doi: 10.1158/0008-5472.CAN-08-3240. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176372 Free PMC article.
Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling.
Segrelles C, Moral M, Lorz C, Santos M, Lu J, Cascallana JL, Lara MF, Carbajal S, Martínez-Cruz AB, García-Escudero R, Beltran L, Segovia JC, Bravo A, DiGiovanni J, Paramio JM. Segrelles C, et al. Among authors: bravo a. Mol Biol Cell. 2008 Jan;19(1):137-49. doi: 10.1091/mbc.e07-08-0764. Epub 2007 Oct 24. Mol Biol Cell. 2008. PMID: 17959825 Free PMC article.
Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis.
Segrelles C, Lu J, Hammann B, Santos M, Moral M, Cascallana JL, Lara MF, Rho O, Carbajal S, Traag J, Beltrán L, Martínez-Cruz AB, García-Escudero R, Lorz C, Ruiz S, Bravo A, Paramio JM, DiGiovanni J. Segrelles C, et al. Among authors: bravo a. Cancer Res. 2007 Nov 15;67(22):10879-88. doi: 10.1158/0008-5472.CAN-07-2564. Cancer Res. 2007. PMID: 18006833
IKKβ-Mediated Resistance to Skin Cancer Development Is Ink4a/Arf-Dependent.
Page A, Bravo A, Suarez-Cabrera C, Alameda JP, Casanova ML, Lorz C, Segrelles C, Segovia JC, Paramio JM, Navarro M, Ramirez A. Page A, et al. Among authors: bravo a. Mol Cancer Res. 2017 Sep;15(9):1255-1264. doi: 10.1158/1541-7786.MCR-17-0157. Epub 2017 Jun 5. Mol Cancer Res. 2017. PMID: 28584022
Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia.
Errazquin R, Page A, Suñol A, Segrelles C, Carrasco E, Peral J, Garrido-Aranda A, Del Marro S, Ortiz J, Lorz C, Minguillon J, Surralles J, Belendez C, Alvarez M, Balmaña J, Bravo A, Ramirez A, Garcia-Escudero R. Errazquin R, et al. Among authors: bravo a. Oral Oncol. 2022 Nov;134:106184. doi: 10.1016/j.oraloncology.2022.106184. Epub 2022 Sep 30. Oral Oncol. 2022. PMID: 36191479 Free article.
784 results