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Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.
Rieusset J, Chauvin MA, Durand A, Bravard A, Laugerette F, Michalski MC, Vidal H. Rieusset J, et al. Among authors: bravard a. Biochem Biophys Res Commun. 2012 Jan 6;417(1):439-45. doi: 10.1016/j.bbrc.2011.11.135. Epub 2011 Dec 7. Biochem Biophys Res Commun. 2012. PMID: 22177958 Free article.
Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance.
Rieusset J, Fauconnier J, Paillard M, Belaidi E, Tubbs E, Chauvin MA, Durand A, Bravard A, Teixeira G, Bartosch B, Michelet M, Theurey P, Vial G, Demion M, Blond E, Zoulim F, Gomez L, Vidal H, Lacampagne A, Ovize M. Rieusset J, et al. Among authors: bravard a. Diabetologia. 2016 Mar;59(3):614-23. doi: 10.1007/s00125-015-3829-8. Epub 2015 Dec 10. Diabetologia. 2016. PMID: 26660890 Free article.
FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction.
Bravard A, Lefai E, Meugnier E, Pesenti S, Disse E, Vouillarmet J, Peretti N, Rabasa-Lhoret R, Laville M, Vidal H, Rieusset J. Bravard A, et al. Diabetes. 2011 Jan;60(1):258-68. doi: 10.2337/db10-0281. Epub 2010 Oct 13. Diabetes. 2011. PMID: 20943749 Free PMC article.
Impact of KRAS G12C mutation in patients with advanced non-squamous non-small cell lung cancer treated with first-line pembrolizumab monotherapy.
Justeau G, Huchot E, Simonneau Y, Roa M, Le Treut J, Le Garff G, Bylicki O, Schott R, Bravard AS, Tiercin M, Lamy R, De Chabot G, Marty A, Moreau D, Locher C, Bernier C, Chouaid C, Descourt R. Justeau G, et al. Among authors: bravard as. Lung Cancer. 2022 Dec;174:45-49. doi: 10.1016/j.lungcan.2022.10.005. Epub 2022 Oct 26. Lung Cancer. 2022. PMID: 36323057
38 results