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Page 1
Disentangling multiple chemical and non-chemical stressors in a lotic ecosystem using a longitudinal approach.
Weitere M, Altenburger R, Anlanger C, Baborowski M, Bärlund I, Beckers LM, Borchardt D, Brack W, Brase L, Busch W, Chatzinotas A, Deutschmann B, Eligehausen J, Frank K, Graeber D, Griebler C, Hagemann J, Herzsprung P, Hollert H, Inostroza PA, Jäger CG, Kallies R, Kamjunke N, Karrasch B, Kaschuba S, Kaus A, Klauer B, Knöller K, Koschorreck M, Krauss M, Kunz JV, Kurz MJ, Liess M, Mages M, Müller C, Muschket M, Musolff A, Norf H, Pöhlein F, Reiber L, Risse-Buhl U, Schramm KW, Schmitt-Jansen M, Schmitz M, Strachauer U, von Tümpling W, Weber N, Wild R, Wolf C, Brauns M. Weitere M, et al. Among authors: brase l. Sci Total Environ. 2021 May 15;769:144324. doi: 10.1016/j.scitotenv.2020.144324. Epub 2020 Dec 25. Sci Total Environ. 2021. PMID: 33482551 Free article.
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.
Eteleeb AM, Novotny BC, Tarraga CS, Sohn C, Dhungel E, Brase L, Nallapu A, Buss J, Farias F, Bergmann K, Bradley J, Norton J, Gentsch J, Wang F, Davis AA, Morris JC, Karch CM, Perrin RJ, Benitez BA, Harari O. Eteleeb AM, et al. Among authors: brase l. PLoS Biol. 2024 Apr 30;22(4):e3002607. doi: 10.1371/journal.pbio.3002607. Online ahead of print. PLoS Biol. 2024. PMID: 38687811 Free article.
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Sheehan PW, Nadarajah CJ, Kanan MF, Patterson JN, Novotny B, Lawrence JH, King MW, Brase L, Inman CE, Yuede CM, Lee J, Patel TK, Harari O, Benitez BA, Davis AA, Musiek ES. Sheehan PW, et al. Among authors: brase l. Neuron. 2023 Aug 2;111(15):2383-2398.e7. doi: 10.1016/j.neuron.2023.05.006. Epub 2023 Jun 13. Neuron. 2023. PMID: 37315555
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.
Brase L, You SF, D'Oliveira Albanus R, Del-Aguila JL, Dai Y, Novotny BC, Soriano-Tarraga C, Dykstra T, Fernandez MV, Budde JP, Bergmann K, Morris JC, Bateman RJ, Perrin RJ, McDade E, Xiong C, Goate AM, Farlow M; Dominantly Inherited Alzheimer Network (DIAN); Sutherland GT, Kipnis J, Karch CM, Benitez BA, Harari O. Brase L, et al. Nat Commun. 2023 Apr 21;14(1):2314. doi: 10.1038/s41467-023-37437-5. Nat Commun. 2023. PMID: 37085492 Free PMC article.
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state.
You SF, Brase L, Filipello F, Iyer AK, Del-Aguila J, He J, D'Oliveira Albanus R, Budde J, Norton J, Gentsch J, Dräger NM, Sattler SM, Kampmann M, Piccio L, Morris JC, Perrin RJ, McDade E; Dominantly Inherited Alzheimer Network; Paul SM, Cashikar AG, Benitez BA, Harari O, Karch CM. You SF, et al. Among authors: brase l. medRxiv [Preprint]. 2023 Feb 8:2023.02.06.23285545. doi: 10.1101/2023.02.06.23285545. medRxiv. 2023. PMID: 36798226 Free PMC article. Preprint.
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: brase l. Neuron. 2023 Jan 18;111(2):202-219.e7. doi: 10.1016/j.neuron.2022.10.022. Epub 2022 Nov 10. Neuron. 2023. PMID: 36368315 Free PMC article.
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.
Da Mesquita S, Papadopoulos Z, Dykstra T, Brase L, Farias FG, Wall M, Jiang H, Kodira CD, de Lima KA, Herz J, Louveau A, Goldman DH, Salvador AF, Onengut-Gumuscu S, Farber E, Dabhi N, Kennedy T, Milam MG, Baker W, Smirnov I, Rich SS; Dominantly Inherited Alzheimer Network; Benitez BA, Karch CM, Perrin RJ, Farlow M, Chhatwal JP, Holtzman DM, Cruchaga C, Harari O, Kipnis J. Da Mesquita S, et al. Among authors: brase l. Nature. 2021 May;593(7858):255-260. doi: 10.1038/s41586-021-03489-0. Epub 2021 Apr 28. Nature. 2021. PMID: 33911285 Free PMC article.
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