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Novel diamides inspired by protein kinase inhibitors as anti-Trypanosoma cruzi agents: in vitro and in vivo evaluations.
Vieira da Silva Torchelsen FK, Fernandes Pedrosa TC, Rodrigues MP, de Aguiar AR, de Oliveira FM, Amarante GW, Sales-Junior PA, Branquinho RT, Gomes da Silva SP, Talvani A, Fonseca Murta SM, Martins FT, Braun RL, Teixeira RR, Furtado Mosqueira VC, Lana M. Vieira da Silva Torchelsen FK, et al. Among authors: branquinho rt. Future Med Chem. 2023 Aug;15(16):1469-1489. doi: 10.4155/fmc-2023-0090. Epub 2023 Aug 31. Future Med Chem. 2023. PMID: 37650735
TcI, TcII and TcVI Trypanosoma cruzi samples from Chagas disease patients with distinct clinical forms and critical analysis of in vitro and in vivo behavior, response to treatment and infection evolution in murine model.
Oliveira MT, Branquinho RT, Alessio GD, Mello CGC, Nogueira-de-Paiva NC, Carneiro CM, Toledo MJO, Reis AB, Martins-Filho OAM, Lana M. Oliveira MT, et al. Among authors: branquinho rt. Acta Trop. 2017 Mar;167:108-120. doi: 10.1016/j.actatropica.2016.11.033. Epub 2016 Nov 28. Acta Trop. 2017. PMID: 27908747
Lychnopholide loaded in surface modified polylactide nanocapsules (LYC-PLA-PEG-NC) cure mice infected by Trypanosoma cruzi strain a prototype of resistance to benznidazole and nifurtimox: First insights of its mechanism of action.
Milagre MM, Torchelsen FKVDS, Pedrosa TCF, Teixeira GM, Sampaio LS, Saúde-Guimarães DA, Branquinho RT, Mosqueira VCF, Lana M. Milagre MM, et al. Among authors: branquinho rt. Exp Parasitol. 2023 Dec;255:108647. doi: 10.1016/j.exppara.2023.108647. Epub 2023 Oct 30. Exp Parasitol. 2023. PMID: 37914151
Lychnopholide in Poly(d,l-Lactide)-Block-Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma cruzi Strain at Acute and Chronic Phases.
Branquinho RT, de Mello CGC, Oliveira MT, Reis LES, Vieira PMA, Saúde-Guimarães DA, Mosqueira VCF, de Lana M. Branquinho RT, et al. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e01937-19. doi: 10.1128/AAC.01937-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31988096 Free PMC article.
In vitro interaction of polyethylene glycol-block-poly(D,L-lactide) nanocapsule devices with host cardiomyoblasts and Trypanosoma cruzi-infective forms.
Siqueira RP, Milagre MM, de Oliveira MA, Branquinho RT, Torchelsen FKV, de Lana M, Machado MGC, Andrade MS, Bahia MT, Mosqueira VCF. Siqueira RP, et al. Among authors: branquinho rt. Parasitol Res. 2022 Oct;121(10):2861-2874. doi: 10.1007/s00436-022-07618-0. Epub 2022 Aug 16. Parasitol Res. 2022. PMID: 35972545
17 results