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Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Gangoso E, Southgate B, Bradley L, Rus S, Galvez-Cancino F, McGivern N, Güç E, Kapourani CA, Byron A, Ferguson KM, Alfazema N, Morrison G, Grant V, Blin C, Sou I, Marques-Torrejon MA, Conde L, Parrinello S, Herrero J, Beck S, Brandner S, Brennan PM, Bertone P, Pollard JW, Quezada SA, Sproul D, Frame MC, Serrels A, Pollard SM. Gangoso E, et al. Among authors: brandner s. Cell. 2021 Apr 29;184(9):2454-2470.e26. doi: 10.1016/j.cell.2021.03.023. Epub 2021 Apr 14. Cell. 2021. PMID: 33857425 Free PMC article.
H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Pathania M, De Jay N, Maestro N, Harutyunyan AS, Nitarska J, Pahlavan P, Henderson S, Mikael LG, Richard-Londt A, Zhang Y, Costa JR, Hébert S, Khazaei S, Ibrahim NS, Herrero J, Riccio A, Albrecht S, Ketteler R, Brandner S, Kleinman CL, Jabado N, Salomoni P. Pathania M, et al. Among authors: brandner s. Cancer Cell. 2017 Nov 13;32(5):684-700.e9. doi: 10.1016/j.ccell.2017.09.014. Epub 2017 Oct 26. Cancer Cell. 2017. PMID: 29107533 Free PMC article.
The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Among authors: brandner s. Nat Commun. 2021 Apr 12;12(1):2184. doi: 10.1038/s41467-021-22225-w. Nat Commun. 2021. PMID: 33846316 Free PMC article.
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Among authors: brandner s. Nat Commun. 2022 Apr 14;13(1):2163. doi: 10.1038/s41467-022-29916-y. Nat Commun. 2022. PMID: 35422055 Free PMC article. No abstract available.
Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro.
Henriquez NV, Forshew T, Tatevossian R, Ellis M, Richard-Loendt A, Rogers H, Jacques TS, Reitboeck PG, Pearce K, Sheer D, Grundy RG, Brandner S. Henriquez NV, et al. Among authors: brandner s. Cancer Res. 2013 Sep 15;73(18):5834-44. doi: 10.1158/0008-5472.CAN-13-1299. Epub 2013 Jul 25. Cancer Res. 2013. PMID: 23887970
A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS.
Amodeo V, A D, Betts J, Bartesaghi S, Zhang Y, Richard-Londt A, Ellis M, Roshani R, Vouri M, Galavotti S, Oberndorfer S, Leite AP, Mackay A, Lampada A, Stratford EW, Li N, Dinsdale D, Grimwade D, Jones C, Nicotera P, Michod D, Brandner S, Salomoni P. Amodeo V, et al. Among authors: brandner s. Cell Rep. 2017 Jul 11;20(2):411-426. doi: 10.1016/j.celrep.2017.06.047. Cell Rep. 2017. PMID: 28700942 Free article.
Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma.
Vinel C, Rosser G, Guglielmi L, Constantinou M, Pomella N, Zhang X, Boot JR, Jones TA, Millner TO, Dumas AA, Rakyan V, Rees J, Thompson JL, Vuononvirta J, Nadkarni S, El Assan T, Aley N, Lin YY, Liu P, Nelander S, Sheer D, Merry CLR, Marelli-Berg F, Brandner S, Marino S. Vinel C, et al. Among authors: brandner s. Nat Commun. 2021 Oct 21;12(1):6130. doi: 10.1038/s41467-021-26297-6. Nat Commun. 2021. PMID: 34675201 Free PMC article.
442 results