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A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.
Nucleic Acids Res. 2024 May 10:gkae368. doi: 10.1093/nar/gkae368. Online ahead of print.
Nucleic Acids Res. 2024.
PMID: 38726879
Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.
Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrison B, Rothstein JD, Khvorova A, Czech MP.
Min K, et al. Among authors: bramato b.
Elife. 2024 Apr 2;12:RP89136. doi: 10.7554/eLife.89136.
Elife. 2024.
PMID: 38564479
Free PMC article.
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A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system.
Belgrad J, Tang Q, Hildebrand S, Summers A, Sapp E, Echeverria D, O'Reilly D, Luu E, Bramato B, Allen S, Cooper D, Alterman J, Yamada K, Aronin N, DiFiglia M, Khvorova A.
Belgrad J, et al. Among authors: bramato b.
bioRxiv [Preprint]. 2023 Dec 19:2023.12.19.572404. doi: 10.1101/2023.12.19.572404.
bioRxiv. 2023.
PMID: 38187561
Free PMC article.
Updated.
Preprint.
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Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, Søgaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yıldız-Altay Ü, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE.
Tang Q, et al. Among authors: bramato b.
Nat Commun. 2023 Nov 4;14(1):7099. doi: 10.1038/s41467-023-42714-4.
Nat Commun. 2023.
PMID: 37925520
Free PMC article.
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Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.
Yenilmez B, Harney S, DiMarzio C, Kelly M, Min K, Echeverria D, Bramato BM, Jackson SO, Reddig K, Kim JK, Khvorova A, Czech MP.
Yenilmez B, et al. Among authors: bramato bm.
bioRxiv [Preprint]. 2023 Jul 5:2023.07.05.547848. doi: 10.1101/2023.07.05.547848.
bioRxiv. 2023.
PMID: 37461560
Free PMC article.
Preprint.
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Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
Hariharan VN, Caiazzi J, Miller R, Ferguson C, Sapp E, Fakih H, Tang Q, Yamada N, Furgal R, Paquette J, Bramato B, McHugh N, Summers A, Lochmann C, Godinho B, Hildebrand S, Echeverria D, Hassler M, Alterman J, DiFiglia M, Aronin N, Khvorova A, Yamada K.
Hariharan VN, et al. Among authors: bramato b.
Res Sq [Preprint]. 2023 Jun 1:rs.3.rs-2987323. doi: 10.21203/rs.3.rs-2987323/v1.
Res Sq. 2023.
PMID: 37398145
Free PMC article.
Preprint.
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Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
Yamada K, Hariharan VN, Caiazzi J, Miller R, Furguson C, Sapp E, Fakih H, Tan Q, Yamada N, Furgal RC, Paquette J, Bramato B, McHugh N, Summers A, Lochmann C, Godinho BMDC, Hildebrand S, Echeverria D, Hassler MR, Alterman JF, DiFiglia M, Aronin N, Khvorova A.
Yamada K, et al. Among authors: bramato b.
bioRxiv [Preprint]. 2023 May 26:2023.05.26.542506. doi: 10.1101/2023.05.26.542506.
bioRxiv. 2023.
PMID: 37292886
Free PMC article.
Preprint.
Item in Clipboard
Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.
Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrision B, Rothstein JD, Khvorova A, Czech MP.
Min K, et al. Among authors: bramato b.
bioRxiv [Preprint]. 2023 Oct 19:2023.05.03.539244. doi: 10.1101/2023.05.03.539244.
bioRxiv. 2023.
PMID: 37205462
Free PMC article.
Updated.
Preprint.
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