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Page 1
Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1.
Redpath NT, Xu Y, Wilson NJ, Fabri LJ, Baca M, Andrews AE, Braley H, Lu P, Ireland C, Ernst RE, Woods A, Forrest G, An Z, Zaller DM, Strohl WR, Luo CS, Czabotar PE, Garrett TP, Hilton DJ, Nash AD, Zhang JG, Nicola NA. Redpath NT, et al. Among authors: braley h. Biochem J. 2013 Apr 15;451(2):165-75. doi: 10.1042/BJ20121819. Biochem J. 2013. PMID: 23384096
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody.
Broughton SE, Hercus TR, Hardy MP, McClure BJ, Nero TL, Dottore M, Huynh H, Braley H, Barry EF, Kan WL, Dhagat U, Scotney P, Hartman D, Busfield SJ, Owczarek CM, Nash AD, Wilson NJ, Parker MW, Lopez AF. Broughton SE, et al. Among authors: braley h. Cell Rep. 2014 Jul 24;8(2):410-9. doi: 10.1016/j.celrep.2014.06.038. Epub 2014 Jul 17. Cell Rep. 2014. PMID: 25043189 Free article.
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors.
Panousis C, Dhagat U, Edwards KM, Rayzman V, Hardy MP, Braley H, Gauvreau GM, Hercus TR, Smith S, Sehmi R, McMillan L, Dottore M, McClure BJ, Fabri LJ, Vairo G, Lopez AF, Parker MW, Nash AD, Wilson NJ, Wilson MJ, Owczarek CM. Panousis C, et al. Among authors: braley h. MAbs. 2016;8(3):436-53. doi: 10.1080/19420862.2015.1119352. Epub 2015 Dec 14. MAbs. 2016. PMID: 26651396 Free PMC article.
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement.
Caminschi I, Proietto AI, Ahmet F, Kitsoulis S, Shin Teh J, Lo JC, Rizzitelli A, Wu L, Vremec D, van Dommelen SL, Campbell IK, Maraskovsky E, Braley H, Davey GM, Mottram P, van de Velde N, Jensen K, Lew AM, Wright MD, Heath WR, Shortman K, Lahoud MH. Caminschi I, et al. Among authors: braley h. Blood. 2008 Oct 15;112(8):3264-73. doi: 10.1182/blood-2008-05-155176. Epub 2008 Jul 30. Blood. 2008. PMID: 18669894 Free PMC article.
The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses.
Lahoud MH, Proietto AI, Ahmet F, Kitsoulis S, Eidsmo L, Wu L, Sathe P, Pietersz S, Chang HW, Walker ID, Maraskovsky E, Braley H, Lew AM, Wright MD, Heath WR, Shortman K, Caminschi I. Lahoud MH, et al. Among authors: braley h. J Immunol. 2009 Jun 15;182(12):7587-94. doi: 10.4049/jimmunol.0900464. J Immunol. 2009. PMID: 19494282
ISCOMATRIX vaccines mediate CD8+ T-cell cross-priming by a MyD88-dependent signaling pathway.
Wilson NS, Yang B, Morelli AB, Koernig S, Yang A, Loeser S, Airey D, Provan L, Hass P, Braley H, Couto S, Drane D, Boyle J, Belz GT, Ashkenazi A, Maraskovsky E. Wilson NS, et al. Among authors: braley h. Immunol Cell Biol. 2012 May;90(5):540-52. doi: 10.1038/icb.2011.71. Epub 2011 Sep 6. Immunol Cell Biol. 2012. PMID: 21894173 Free PMC article.
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