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Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.
Arsic N, Slatter T, Gadea G, Villain E, Fournet A, Kazantseva M, Allemand F, Sibille N, Seveno M, de Rossi S, Mehta S, Urbach S, Bourdon JC, Bernado P, Kajava AV, Braithwaite A, Roux P. Arsic N, et al. Among authors: braithwaite a. Nat Commun. 2021 Sep 15;12(1):5463. doi: 10.1038/s41467-021-25550-2. Nat Commun. 2021. PMID: 34526502 Free PMC article.
Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform.
Slatter TL, Hung N, Campbell H, Rubio C, Mehta R, Renshaw P, Williams G, Wilson M, Engelmann A, Jeffs A, Royds JA, Baird MA, Braithwaite AW. Slatter TL, et al. Among authors: braithwaite aw. Blood. 2011 May 12;117(19):5166-77. doi: 10.1182/blood-2010-11-321851. Epub 2011 Mar 16. Blood. 2011. PMID: 21411755 Free article.
The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.
Royds JA, Al Nadaf S, Wiles AK, Chen YJ, Ahn A, Shaw A, Bowie S, Lam F, Baguley BC, Braithwaite AW, MacFarlane MR, Hung NA, Slatter TL. Royds JA, et al. Among authors: braithwaite aw. PLoS One. 2011;6(10):e26737. doi: 10.1371/journal.pone.0026737. Epub 2011 Oct 26. PLoS One. 2011. PMID: 22046342 Free PMC article.
Does Δ133p53 isoform trigger inflammation and autoimmunity?
Campbell HG, Slatter TL, Jeffs A, Mehta R, Rubio C, Baird M, Braithwaite AW. Campbell HG, et al. Among authors: braithwaite aw. Cell Cycle. 2012 Feb 1;11(3):446-50. doi: 10.4161/cc.11.3.19054. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22262184
167 results