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An ongoing role of α-calcitonin gene-related peptide as part of a protective network against hypertension, vascular hypertrophy, and oxidative stress.
Smillie SJ, King R, Kodji X, Outzen E, Pozsgai G, Fernandes E, Marshall N, de Winter P, Heads RJ, Dessapt-Baradez C, Gnudi L, Sams A, Shah AM, Siow RC, Brain SD. Smillie SJ, et al. Among authors: brain sd. Hypertension. 2014 May;63(5):1056-62. doi: 10.1161/HYPERTENSIONAHA.113.02517. Epub 2014 Feb 10. Hypertension. 2014. PMID: 24516108
Calcitonin gene-related peptide: physiology and pathophysiology.
Russell FA, King R, Smillie SJ, Kodji X, Brain SD. Russell FA, et al. Among authors: brain sd. Physiol Rev. 2014 Oct;94(4):1099-142. doi: 10.1152/physrev.00034.2013. Physiol Rev. 2014. PMID: 25287861 Free PMC article. Review.
TRPA1 is essential for the vascular response to environmental cold exposure.
Aubdool AA, Graepel R, Kodji X, Alawi KM, Bodkin JV, Srivastava S, Gentry C, Heads R, Grant AD, Fernandes ES, Bevan S, Brain SD. Aubdool AA, et al. Among authors: brain sd. Nat Commun. 2014 Dec 11;5:5732. doi: 10.1038/ncomms6732. Nat Commun. 2014. PMID: 25501034 Free PMC article.
Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner.
Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C, Smillie SJ, Bevan S, Keeble JE, Malcangio M, Brain SD. Fernandes ES, et al. Among authors: brain sd. Arthritis Res Ther. 2016 Jan 11;18:7. doi: 10.1186/s13075-015-0905-x. Arthritis Res Ther. 2016. PMID: 26754745 Free PMC article.
Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.
Alawi KM, Russell FA, Aubdool AA, Srivastava S, Riffo-Vasquez Y, Baldissera L Jr, Thakore P, Saleque N, Fernandes ES, Walsh DA, Brain SD. Alawi KM, et al. Among authors: brain sd. Ann Rheum Dis. 2017 Jan;76(1):252-260. doi: 10.1136/annrheumdis-2015-208886. Epub 2016 May 10. Ann Rheum Dis. 2017. PMID: 27165180 Free PMC article.
A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy, and Heart Failure.
Aubdool AA, Thakore P, Argunhan F, Smillie SJ, Schnelle M, Srivastava S, Alawi KM, Wilde E, Mitchell J, Farrell-Dillon K, Richards DA, Maltese G, Siow RC, Nandi M, Clark JE, Shah AM, Sams A, Brain SD. Aubdool AA, et al. Among authors: brain sd. Circulation. 2017 Jul 25;136(4):367-383. doi: 10.1161/CIRCULATIONAHA.117.028388. Epub 2017 Apr 26. Circulation. 2017. PMID: 28446517 Free PMC article.
227 results