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DISC1, PDE4B, and NDE1 at the centrosome and synapse.
Bradshaw NJ, Ogawa F, Antolin-Fontes B, Chubb JE, Carlyle BC, Christie S, Claessens A, Porteous DJ, Millar JK. Bradshaw NJ, et al. Biochem Biophys Res Commun. 2008 Dec 26;377(4):1091-6. doi: 10.1016/j.bbrc.2008.10.120. Epub 2008 Nov 5. Biochem Biophys Res Commun. 2008. PMID: 18983980
Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions.
Gowert NS, Krüger I, Klier M, Donner L, Kipkeew F, Gliem M, Bradshaw NJ, Lutz D, Köber S, Langer H, Jander S, Jurk K, Frotscher M, Korth C, Bock HH, Elvers M. Gowert NS, et al. Among authors: bradshaw nj. Cell Signal. 2017 Dec;40:210-221. doi: 10.1016/j.cellsig.2017.09.016. Epub 2017 Sep 21. Cell Signal. 2017. PMID: 28943410
A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations.
Yerabham ASK, Mas PJ, Decker C, Soares DC, Weiergräber OH, Nagel-Steger L, Willbold D, Hart DJ, Bradshaw NJ, Korth C. Yerabham ASK, et al. Among authors: bradshaw nj. J Biol Chem. 2017 Apr 21;292(16):6468-6477. doi: 10.1074/jbc.M116.773903. Epub 2017 Mar 1. J Biol Chem. 2017. PMID: 28249940 Free PMC article.
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution.
Soares DC, Bradshaw NJ, Zou J, Kennaway CK, Hamilton RS, Chen ZA, Wear MA, Blackburn EA, Bramham J, Böttcher B, Millar JK, Barlow PN, Walkinshaw MD, Rappsilber J, Porteous DJ. Soares DC, et al. Among authors: bradshaw nj. J Biol Chem. 2012 Sep 21;287(39):32381-93. doi: 10.1074/jbc.M112.393439. Epub 2012 Jul 27. J Biol Chem. 2012. PMID: 22843697 Free PMC article.
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, García Á, Requena JR, Hipolito M, Rai N, Nwulia E, Henning U, Ferrea S, Luckhaus C, Ekelund J, Veijola J, Järvelin MR, Hennah W, Korth C. Bader V, et al. Among authors: bradshaw nj. Hum Mol Genet. 2012 Oct 15;21(20):4406-18. doi: 10.1093/hmg/dds273. Epub 2012 Jul 13. Hum Mol Genet. 2012. PMID: 22798627 Free PMC article.
36 results