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Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations.
Woeste MA, Stern S, Raju DN, Grahn E, Dittmann D, Gutbrod K, Dörmann P, Hansen JN, Schonauer S, Marx CE, Hamzeh H, Körschen HG, Aerts JMFG, Bönigk W, Endepols H, Sandhoff R, Geyer M, Berger TK, Bradke F, Wachten D. Woeste MA, et al. Among authors: bradke f. J Biol Chem. 2019 Mar 15;294(11):3853-3871. doi: 10.1074/jbc.RA118.006311. Epub 2019 Jan 20. J Biol Chem. 2019. PMID: 30662006 Free PMC article.
ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS.
Tedeschi A, Dupraz S, Curcio M, Laskowski CJ, Schaffran B, Flynn KC, Santos TE, Stern S, Hilton BJ, Larson MJE, Gurniak CB, Witke W, Bradke F. Tedeschi A, et al. Among authors: bradke f. Neuron. 2019 Sep 25;103(6):1073-1085.e6. doi: 10.1016/j.neuron.2019.07.007. Epub 2019 Aug 7. Neuron. 2019. PMID: 31400829 Free PMC article.
An assay to image neuronal microtubule dynamics in mice.
Kleele T, Marinković P, Williams PR, Stern S, Weigand EE, Engerer P, Naumann R, Hartmann J, Karl RM, Bradke F, Bishop D, Herms J, Konnerth A, Kerschensteiner M, Godinho L, Misgeld T. Kleele T, et al. Among authors: bradke f. Nat Commun. 2014 Sep 12;5:4827. doi: 10.1038/ncomms5827. Nat Commun. 2014. PMID: 25219969 Free PMC article.
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.
Alecu I, Tedeschi A, Behler N, Wunderling K, Lamberz C, Lauterbach MA, Gaebler A, Ernst D, Van Veldhoven PP, Al-Amoudi A, Latz E, Othman A, Kuerschner L, Hornemann T, Bradke F, Thiele C, Penno A. Alecu I, et al. Among authors: bradke f. J Lipid Res. 2017 Jan;58(1):42-59. doi: 10.1194/jlr.M068676. Epub 2016 Nov 23. J Lipid Res. 2017. PMID: 27881717 Free PMC article.
Cdc42 regulates cofilin during the establishment of neuronal polarity.
Garvalov BK, Flynn KC, Neukirchen D, Meyn L, Teusch N, Wu X, Brakebusch C, Bamburg JR, Bradke F. Garvalov BK, et al. Among authors: bradke f. J Neurosci. 2007 Nov 28;27(48):13117-29. doi: 10.1523/JNEUROSCI.3322-07.2007. J Neurosci. 2007. PMID: 18045906 Free PMC article.
102 results