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Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol.
Dorrington MG, Bradfield CJ, Lack JB, Lin B, Liang JJ, Starr T, Ernst O, Gross JL, Sun J, Miller AH, Steele-Mortimer O, Fraser IDC. Dorrington MG, et al. Among authors: bradfield cj. PLoS Pathog. 2021 Mar 8;17(3):e1009395. doi: 10.1371/journal.ppat.1009395. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33684179 Free PMC article.
A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation.
Ernst O, Sun J, Lin B, Banoth B, Dorrington MG, Liang J, Schwarz B, Stromberg KA, Katz S, Vayttaden SJ, Bradfield CJ, Slepushkina N, Rice CM, Buehler E, Khillan JS, McVicar DW, Bosio CM, Bryant CE, Sutterwala FS, Martin SE, Lal-Nag M, Fraser IDC. Ernst O, et al. Among authors: bradfield cj. Sci Signal. 2021 Aug 3;14(694):eabe0387. doi: 10.1126/scisignal.abe0387. Sci Signal. 2021. PMID: 34344832 Free PMC article.
Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol.
Dorrington MG, Bradfield CJ, Lack JB, Lin B, John SP, Liang JJ, Starr T, Ernst O, Gross JL, Sun J, Miller AH, Steele-Mortimer O, Fraser IDC. Dorrington MG, et al. Among authors: bradfield cj. PLoS Pathog. 2021 Aug 4;17(8):e1009821. doi: 10.1371/journal.ppat.1009821. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34347853 Free PMC article.
Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection.
John SP, Singh A, Sun J, Pierre MJ, Alsalih L, Lipsey C, Traore Z, Balcom-Luker S, Bradfield CJ, Song J, Markowitz TE, Smelkinson M, Ferrer M, Fraser IDC. John SP, et al. Among authors: bradfield cj. Cell Rep. 2022 Oct 4;41(1):111441. doi: 10.1016/j.celrep.2022.111441. Epub 2022 Sep 15. Cell Rep. 2022. PMID: 36179680 Free PMC article.
A human apolipoprotein L with detergent-like activity kills intracellular pathogens.
Gaudet RG, Zhu S, Halder A, Kim BH, Bradfield CJ, Huang S, Xu D, Mamiñska A, Nguyen TN, Lazarou M, Karatekin E, Gupta K, MacMicking JD. Gaudet RG, et al. Among authors: bradfield cj. Science. 2021 Jul 16;373(6552):eabf8113. doi: 10.1126/science.abf8113. Science. 2021. PMID: 34437126 Free PMC article.
14 results