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A human apolipoprotein L with detergent-like activity kills intracellular pathogens.
Gaudet RG, Zhu S, Halder A, Kim BH, Bradfield CJ, Huang S, Xu D, Mamiñska A, Nguyen TN, Lazarou M, Karatekin E, Gupta K, MacMicking JD. Gaudet RG, et al. Among authors: bradfield cj. Science. 2021 Jul 16;373(6552):eabf8113. doi: 10.1126/science.abf8113. Science. 2021. PMID: 34437126 Free PMC article.
Crossing the Rubicon: new roads lead to host defense.
Bradfield CJ, Kim BH, MacMicking JD. Bradfield CJ, et al. Cell Host Microbe. 2012 Mar 15;11(3):221-3. doi: 10.1016/j.chom.2012.02.005. Cell Host Microbe. 2012. PMID: 22423961 Free PMC article.
IFN-inducible GTPases in host cell defense.
Kim BH, Shenoy AR, Kumar P, Bradfield CJ, MacMicking JD. Kim BH, et al. Among authors: bradfield cj. Cell Host Microbe. 2012 Oct 18;12(4):432-44. doi: 10.1016/j.chom.2012.09.007. Cell Host Microbe. 2012. PMID: 23084913 Free PMC article. Review.
Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol.
Dorrington MG, Bradfield CJ, Lack JB, Lin B, Liang JJ, Starr T, Ernst O, Gross JL, Sun J, Miller AH, Steele-Mortimer O, Fraser IDC. Dorrington MG, et al. Among authors: bradfield cj. PLoS Pathog. 2021 Mar 8;17(3):e1009395. doi: 10.1371/journal.ppat.1009395. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33684179 Free PMC article.
A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation.
Ernst O, Sun J, Lin B, Banoth B, Dorrington MG, Liang J, Schwarz B, Stromberg KA, Katz S, Vayttaden SJ, Bradfield CJ, Slepushkina N, Rice CM, Buehler E, Khillan JS, McVicar DW, Bosio CM, Bryant CE, Sutterwala FS, Martin SE, Lal-Nag M, Fraser IDC. Ernst O, et al. Among authors: bradfield cj. Sci Signal. 2021 Aug 3;14(694):eabe0387. doi: 10.1126/scisignal.abe0387. Sci Signal. 2021. PMID: 34344832 Free PMC article.
15 results