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Hypoxia induced deregulation of sphingolipids in colon cancer is a prognostic marker for patient outcome.
El Hindi K, Brachtendorf S, Hartel JC, Renné C, Birod K, Schilling K, Labocha S, Thomas D, Ferreirós N, Hahnefeld L, Dorochow E, Del Turco D, Deller T, Scholich K, Fuhrmann DC, Weigert A, Brüne B, Geisslinger G, Wittig I, Link KH, Grösch S. El Hindi K, et al. Among authors: brachtendorf s. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166906. doi: 10.1016/j.bbadis.2023.166906. Epub 2023 Oct 4. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37802156 Free article.
Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy.
Brachtendorf S, Wanger RA, Birod K, Thomas D, Trautmann S, Wegner MS, Fuhrmann DC, Brüne B, Geisslinger G, Grösch S. Brachtendorf S, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1214-1227. doi: 10.1016/j.bbalip.2018.07.011. Epub 2018 Jul 27. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 30059758
Ceramide synthases in cancer therapy and chemoresistance.
Brachtendorf S, El-Hindi K, Grösch S. Brachtendorf S, et al. Prog Lipid Res. 2019 Apr;74:160-185. doi: 10.1016/j.plipres.2019.04.002. Epub 2019 Apr 4. Prog Lipid Res. 2019. PMID: 30953657 Review.
The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated.
Bazarganipour S, Hausmann J, Oertel S, El-Hindi K, Brachtendorf S, Blumenstein I, Kubesch A, Sprinzl K, Birod K, Hahnefeld L, Trautmann S, Thomas D, Herrmann E, Geisslinger G, Schiffmann S, Grösch S. Bazarganipour S, et al. Among authors: brachtendorf s. J Clin Med. 2019 Jul 4;8(7):971. doi: 10.3390/jcm8070971. J Clin Med. 2019. PMID: 31277430 Free PMC article.
T-Cell-Specific CerS4 Depletion Prolonged Inflammation and Enhanced Tumor Burden in the AOM/DSS-Induced CAC Model.
El-Hindi K, Brachtendorf S, Hartel JC, Oertel S, Birod K, Merz N, Trautmann S, Thomas D, Weigert A, Schäufele TJ, Scholich K, Schiffmann S, Ulshöfer T, Utermöhlen O, Grösch S. El-Hindi K, et al. Among authors: brachtendorf s. Int J Mol Sci. 2022 Feb 7;23(3):1866. doi: 10.3390/ijms23031866. Int J Mol Sci. 2022. PMID: 35163788 Free PMC article.
GPER1 influences cellular homeostasis and cytostatic drug resistance via influencing long chain ceramide synthesis in breast cancer cells.
Wegner MS, Gruber L, Schömel N, Trautmann S, Brachtendorf S, Fuhrmann D, Schreiber Y, Olesch C, Brüne B, Geisslinger G, Grösch S. Wegner MS, et al. Among authors: brachtendorf s. Int J Biochem Cell Biol. 2019 Jul;112:95-106. doi: 10.1016/j.biocel.2019.05.002. Epub 2019 May 11. Int J Biochem Cell Biol. 2019. PMID: 31082617
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