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A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors.
Reis H, Pütter C, Megger DA, Bracht T, Weber F, Hoffmann AC, Bertram S, Wohlschläger J, Hagemann S, Eisenacher M, Scherag A, Schlaak JF, Canbay A, Meyer HE, Sitek B, Baba HA. Reis H, et al. Among authors: bracht t. Biochim Biophys Acta. 2015 Jun;1854(6):641-50. doi: 10.1016/j.bbapap.2014.10.024. Epub 2014 Nov 5. Biochim Biophys Acta. 2015. PMID: 25448011
Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study.
Megger DA, Bracht T, Kohl M, Ahrens M, Naboulsi W, Weber F, Hoffmann AC, Stephan C, Kuhlmann K, Eisenacher M, Schlaak JF, Baba HA, Meyer HE, Sitek B. Megger DA, et al. Among authors: bracht t. Mol Cell Proteomics. 2013 Jul;12(7):2006-20. doi: 10.1074/mcp.M113.028027. Epub 2013 Mar 5. Mol Cell Proteomics. 2013. PMID: 23462207 Free PMC article.
A practical data processing workflow for multi-OMICS projects.
Kohl M, Megger DA, Trippler M, Meckel H, Ahrens M, Bracht T, Weber F, Hoffmann AC, Baba HA, Sitek B, Schlaak JF, Meyer HE, Stephan C, Eisenacher M. Kohl M, et al. Among authors: bracht t. Biochim Biophys Acta. 2014 Jan;1844(1 Pt A):52-62. doi: 10.1016/j.bbapap.2013.02.029. Epub 2013 Mar 15. Biochim Biophys Acta. 2014. PMID: 23501674 Free article.
Label-free quantification in clinical proteomics.
Megger DA, Bracht T, Meyer HE, Sitek B. Megger DA, et al. Among authors: bracht t. Biochim Biophys Acta. 2013 Aug;1834(8):1581-90. doi: 10.1016/j.bbapap.2013.04.001. Epub 2013 Apr 6. Biochim Biophys Acta. 2013. PMID: 23567906 Review.
Analysis of U2 small nuclear RNA fragments in the bile differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders.
Baraniskin A, Nöpel-Dünnebacke S, Schumacher B, Gerges C, Bracht T, Sitek B, Meyer HE, Gerken G, Dechene A, Schlaak JF, Schroers R, Pox C, Schmiegel W, Hahn SA. Baraniskin A, et al. Among authors: bracht t. Dig Dis Sci. 2014 Jul;59(7):1436-41. doi: 10.1007/s10620-014-3034-5. Epub 2014 Jan 31. Dig Dis Sci. 2014. PMID: 24482036
Identification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma.
Padden J, Megger DA, Bracht T, Reis H, Ahrens M, Kohl M, Eisenacher M, Schlaak JF, Canbay AE, Weber F, Hoffmann AC, Kuhlmann K, Meyer HE, Baba HA, Sitek B. Padden J, et al. Among authors: bracht t. Mol Cell Proteomics. 2014 Oct;13(10):2661-72. doi: 10.1074/mcp.M113.034942. Epub 2014 Jul 17. Mol Cell Proteomics. 2014. PMID: 25034945 Free PMC article.
Analysis of disease-associated protein expression using quantitative proteomics—fibulin-5 is expressed in association with hepatic fibrosis.
Bracht T, Schweinsberg V, Trippler M, Kohl M, Ahrens M, Padden J, Naboulsi W, Barkovits K, Megger DA, Eisenacher M, Borchers CH, Schlaak JF, Hoffmann AC, Weber F, Baba HA, Meyer HE, Sitek B. Bracht T, et al. J Proteome Res. 2015 May 1;14(5):2278-86. doi: 10.1021/acs.jproteome.5b00053. Epub 2015 Apr 6. J Proteome Res. 2015. PMID: 25807371
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