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The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil.
Cell Biol Toxicol. 2023 Oct;39(5):2401-2419. doi: 10.1007/s10565-022-09731-3. Epub 2022 May 24.
Cell Biol Toxicol. 2023.
PMID: 35608750
Free PMC article.
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3.
Wachholz V, Mustafa AM, Zeyn Y, Henninger SJ, Beyer M, Dzulko M, Piée-Staffa A, Brachetti C, Haehnel PS, Sellmer A, Mahboobi S, Kindler T, Brenner W, Nikolova T, Krämer OH.
Wachholz V, et al. Among authors: brachetti c.
Arch Toxicol. 2022 Jan;96(1):177-193. doi: 10.1007/s00204-021-03174-1. Epub 2021 Oct 19.
Arch Toxicol. 2022.
PMID: 34665271
Free PMC article.
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Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells.
Fischer MA, Mustafa AM, Hausmann K, Ashry R, Kansy AG, Liebl MC, Brachetti C, Piée-Staffa A, Zessin M, Ibrahim HS, Hofmann TG, Schutkowski M, Sippl W, Krämer OH.
Fischer MA, et al. Among authors: brachetti c.
J Adv Res. 2023 Jul 17:S2090-1232(23)00197-2. doi: 10.1016/j.jare.2023.07.005. Online ahead of print.
J Adv Res. 2023.
PMID: 37467961
Free article.
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Lovastatin causes sensitization of HeLa cells to ionizing radiation-induced apoptosis by the abrogation of G2 blockage.
Fritz G, Brachetti C, Kaina B.
Fritz G, et al. Among authors: brachetti c.
Int J Radiat Biol. 2003 Aug;79(8):601-10. doi: 10.1080/09553000310001609233.
Int J Radiat Biol. 2003.
PMID: 14555343
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Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters.
Fritz G, Brachetti C, Bahlmann F, Schmidt M, Kaina B.
Fritz G, et al. Among authors: brachetti c.
Br J Cancer. 2002 Sep 9;87(6):635-44. doi: 10.1038/sj.bjc.6600510.
Br J Cancer. 2002.
PMID: 12237774
Free PMC article.
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Progression of breast tumors is accompanied by a decrease in expression of the Rho guanine exchange factor Tiam1.
Stebel A, Brachetti C, Kunkel M, Schmidt M, Fritz G.
Stebel A, et al. Among authors: brachetti c.
Oncol Rep. 2009 Jan;21(1):217-22.
Oncol Rep. 2009.
PMID: 19082465
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