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Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells.
Hallal R, Nehme R, Brachet-Botineau M, Nehme A, Dakik H, Deynoux M, Dello Sbarba P, Levern Y, Zibara K, Gouilleux F, Mazurier F. Hallal R, et al. Among authors: brachet botineau m. J Cell Mol Med. 2020 Sep;24(17):10052-10062. doi: 10.1111/jcmm.15612. Epub 2020 Jul 15. J Cell Mol Med. 2020. PMID: 32667731 Free PMC article.
Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses.
Bourgeais J, Ishac N, Medrzycki M, Brachet-Botineau M, Desbourdes L, Gouilleux-Gruart V, Pecnard E, Rouleux-Bonnin F, Gyan E, Domenech J, Mazurier F, Moriggl R, Bunting KD, Herault O, Gouilleux F. Bourgeais J, et al. Oncotarget. 2017 Jun 27;8(26):41876-41889. doi: 10.18632/oncotarget.11480. Oncotarget. 2017. PMID: 27566554 Free PMC article.
Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.
Guillon J, Denevault-Sabourin C, Chevret E, Brachet-Botineau M, Milano V, Guédin-Beaurepaire A, Moreau S, Ronga L, Savrimoutou S, Rubio S, Ferrer J, Lamarche J, Mergny JL, Viaud-Massuard MC, Ranz M, Largy E, Gabelica V, Rosu F, Gouilleux F, Desplat V. Guillon J, et al. Among authors: brachet botineau m. Arch Pharm (Weinheim). 2021 Aug;354(8):e2000450. doi: 10.1002/ardp.202000450. Epub 2021 Apr 14. Arch Pharm (Weinheim). 2021. PMID: 33852185
Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody-drug conjugates.
Bryden F, Martin C, Letast S, Lles E, Viéitez-Villemin I, Rousseau A, Colas C, Brachet-Botineau M, Allard-Vannier E, Larbouret C, Viaud-Massuard MC, Joubert N. Bryden F, et al. Among authors: brachet botineau m. Org Biomol Chem. 2018 Mar 14;16(11):1882-1889. doi: 10.1039/c7ob02780j. Org Biomol Chem. 2018. PMID: 29473076
12 results