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21 results

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Page 1
Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial.
Gerwin N, Scotti C, Halleux C, Fornaro M, Elliott J, Zhang Y, Johnson K, Shi J, Walter S, Li Y, Jacobi C, Laplanche N, Belaud M, Paul J, Glowacki G, Peters T, Wharton KA Jr, Vostiar I, Polus F, Kramer I, Guth S, Seroutou A, Choudhury S, Laurent D, Gimbel J, Goldhahn J, Schieker M, Brachat S, Roubenoff R, Kneissel M. Gerwin N, et al. Among authors: brachat s. Nat Med. 2022 Dec;28(12):2633-2645. doi: 10.1038/s41591-022-02059-9. Epub 2022 Dec 1. Nat Med. 2022. PMID: 36456835 Free PMC article. Clinical Trial.
Continuous Digital Monitoring of Walking Speed in Frail Elderly Patients: Noninterventional Validation Study and Longitudinal Clinical Trial.
Mueller A, Hoefling HA, Muaremi A, Praestgaard J, Walsh LC, Bunte O, Huber RM, Fürmetz J, Keppler AM, Schieker M, Böcker W, Roubenoff R, Brachat S, Rooks DS, Clay I. Mueller A, et al. Among authors: brachat s. JMIR Mhealth Uhealth. 2019 Nov 27;7(11):e15191. doi: 10.2196/15191. JMIR Mhealth Uhealth. 2019. PMID: 31774406 Free PMC article.
GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
Egerman MA, Cadena SM, Gilbert JA, Meyer A, Nelson HN, Swalley SE, Mallozzi C, Jacobi C, Jennings LL, Clay I, Laurent G, Ma S, Brachat S, Lach-Trifilieff E, Shavlakadze T, Trendelenburg AU, Brack AS, Glass DJ. Egerman MA, et al. Among authors: brachat s. Cell Metab. 2015 Jul 7;22(1):164-74. doi: 10.1016/j.cmet.2015.05.010. Epub 2015 May 19. Cell Metab. 2015. PMID: 26001423 Free PMC article.
STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia.
Morozzi G, Rothen J, Toussaint G, De Lange K, Westritschnig K, Doelemeyer A, Ueberschlag VP, Kahle P, Lambert C, Obrecht M, Beckmann N, Ritter V, Panesar M, Stauffer D, Garnier I, Mueller M, Guerini D, Keller CG, Knehr J, Roma G, Bidinosti M, Brachat S, Morvan F, Fornaro M. Morozzi G, et al. Among authors: brachat s. iScience. 2021 Nov 14;24(12):103434. doi: 10.1016/j.isci.2021.103434. eCollection 2021 Dec 17. iScience. 2021. PMID: 34877494 Free PMC article.
Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.
Giorgetti E, Panesar M, Zhang Y, Joller S, Ronco M, Obrecht M, Lambert C, Accart N, Beckmann N, Doelemeyer A, Perrot L, Fruh I, Mueller M, Pierrel E, Summermatter S, Bidinosti M, Shimshek DR, Brachat S, Nash M. Giorgetti E, et al. Among authors: brachat s. Cell Rep. 2019 Nov 5;29(6):1539-1554.e7. doi: 10.1016/j.celrep.2019.10.003. Cell Rep. 2019. PMID: 31693894 Free article.
Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia.
Ibebunjo C, Chick JM, Kendall T, Eash JK, Li C, Zhang Y, Vickers C, Wu Z, Clarke BA, Shi J, Cruz J, Fournier B, Brachat S, Gutzwiller S, Ma Q, Markovits J, Broome M, Steinkrauss M, Skuba E, Galarneau JR, Gygi SP, Glass DJ. Ibebunjo C, et al. Among authors: brachat s. Mol Cell Biol. 2013 Jan;33(2):194-212. doi: 10.1128/MCB.01036-12. Epub 2012 Oct 29. Mol Cell Biol. 2013. PMID: 23109432 Free PMC article.
Ten simple rules to power drug discovery with data science.
Ferrero E, Brachat S, Jenkins JL, Marc P, Skewes-Cox P, Altshuler RC, Gubser Keller C, Kauffmann A, Sassaman EK, Laramie JM, Schoeberl B, Borowsky ML, Stiefl N. Ferrero E, et al. Among authors: brachat s. PLoS Comput Biol. 2020 Aug 27;16(8):e1008126. doi: 10.1371/journal.pcbi.1008126. eCollection 2020 Aug. PLoS Comput Biol. 2020. PMID: 32853229 Free PMC article. No abstract available.
21 results