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Page 1
Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials.
Dienstmann R, Garralda E, Aguilar S, Sala G, Viaplana C, Ruiz-Pace F, González-Zorelle J, Grazia LoGiacco D, Ogbah Z, Ramos Masdeu L, Mancuso F, Fasani R, Jimenez J, Martinez P, Oaknin A, Saura C, Oliveira M, Balmaña J, Carles J, Macarulla T, Elez E, Alsina M, Braña I, Felip E, Tabernero J, Rodon J, Nuciforo P, Vivancos A. Dienstmann R, et al. Among authors: brana i. JCO Precis Oncol. 2020 May 14;4:PO.19.00398. doi: 10.1200/PO.19.00398. eCollection 2020. JCO Precis Oncol. 2020. PMID: 32923891 Free PMC article.
Angiosarcoma of the ovary: is it always a lethal disease?
Serrano C, García Á, Brana I, Pérez-Benavente A, Oaknin A. Serrano C, et al. Among authors: brana i. J Clin Oncol. 2010 Nov 20;28(33):e675-7. doi: 10.1200/JCO.2010.30.0830. Epub 2010 Sep 7. J Clin Oncol. 2010. PMID: 20823420 No abstract available.
Cardiotoxicity.
Brana I, Tabernero J. Brana I, et al. Ann Oncol. 2010 Oct;21 Suppl 7:vii173-9. doi: 10.1093/annonc/mdq295. Ann Oncol. 2010. PMID: 20943611 Free article. Review.
Phase I dose-escalation and -expansion study of buparlisib (BKM120), an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors.
Rodon J, Braña I, Siu LL, De Jonge MJ, Homji N, Mills D, Di Tomaso E, Sarr C, Trandafir L, Massacesi C, Eskens F, Bendell JC. Rodon J, et al. Among authors: brana i. Invest New Drugs. 2014 Aug;32(4):670-81. doi: 10.1007/s10637-014-0082-9. Epub 2014 Mar 21. Invest New Drugs. 2014. PMID: 24652201 Clinical Trial.
Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study.
Brana I, Calles A, LoRusso PM, Yee LK, Puchalski TA, Seetharam S, Zhong B, de Boer CJ, Tabernero J, Calvo E. Brana I, et al. Target Oncol. 2015 Mar;10(1):111-23. doi: 10.1007/s11523-014-0320-2. Epub 2014 Jun 15. Target Oncol. 2015. PMID: 24928772 Clinical Trial.
First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer.
Shapiro GI, Bell-McGuinn KM, Molina JR, Bendell J, Spicer J, Kwak EL, Pandya SS, Millham R, Borzillo G, Pierce KJ, Han L, Houk BE, Gallo JD, Alsina M, Braña I, Tabernero J. Shapiro GI, et al. Among authors: brana i. Clin Cancer Res. 2015 Apr 15;21(8):1888-95. doi: 10.1158/1078-0432.CCR-14-1306. Epub 2015 Feb 4. Clin Cancer Res. 2015. PMID: 25652454 Free PMC article. Clinical Trial.
A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer.
Wainberg ZA, Alsina M, Soares HP, Braña I, Britten CD, Del Conte G, Ezeh P, Houk B, Kern KA, Leong S, Pathan N, Pierce KJ, Siu LL, Vermette J, Tabernero J. Wainberg ZA, et al. Among authors: brana i. Target Oncol. 2017 Dec;12(6):775-785. doi: 10.1007/s11523-017-0530-5. Target Oncol. 2017. PMID: 29067643 Free PMC article. Clinical Trial.
New clinical trial designs in the era of precision medicine.
Garralda E, Dienstmann R, Piris-Giménez A, Braña I, Rodon J, Tabernero J. Garralda E, et al. Among authors: brana i. Mol Oncol. 2019 Mar;13(3):549-557. doi: 10.1002/1878-0261.12465. Epub 2019 Feb 22. Mol Oncol. 2019. PMID: 30698321 Free PMC article. Review.
94 results