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Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning.
Zorbaz T, Mišetić P, Probst N, Žunec S, Zandona A, Mendaš G, Micek V, Maček Hrvat N, Katalinić M, Braïki A, Jean L, Renard PY, Gabelica Marković V, Kovarik Z. Zorbaz T, et al. Among authors: braiki a. ACS Chem Neurosci. 2020 Apr 1;11(7):1072-1084. doi: 10.1021/acschemneuro.0c00032. Epub 2020 Mar 11. ACS Chem Neurosci. 2020. PMID: 32105443
Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration.
Zorbaz T, Braïki A, Maraković N, Renou J, de la Mora E, Maček Hrvat N, Katalinić M, Silman I, Sussman JL, Mercey G, Gomez C, Mougeot R, Pérez B, Baati R, Nachon F, Weik M, Jean L, Kovarik Z, Renard PY. Zorbaz T, et al. Among authors: braiki a. Chemistry. 2018 Jul 5;24(38):9675-9691. doi: 10.1002/chem.201801394. Epub 2018 Jun 8. Chemistry. 2018. PMID: 29672968
Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection.
Pashirova TN, Braïki A, Zueva IV, Petrov KA, Babaev VM, Burilova EA, Samarkina DA, Rizvanov IK, Souto EB, Jean L, Renard PY, Masson P, Zakharova LY, Sinyashin OG. Pashirova TN, et al. Among authors: braiki a. J Control Release. 2018 Nov 28;290:102-111. doi: 10.1016/j.jconrel.2018.10.010. Epub 2018 Oct 9. J Control Release. 2018. PMID: 30308259