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GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton.
Wolf C, Pouya A, Bitar S, Pfeiffer A, Bueno D, Rojas-Charry L, Arndt S, Gomez-Zepeda D, Tenzer S, Bello FD, Vianello C, Ritz S, Schwirz J, Dobrindt K, Peitz M, Hanschmann EM, Mencke P, Boussaad I, Silies M, Brüstle O, Giacomello M, Krüger R, Methner A. Wolf C, et al. Among authors: brustle o. Commun Biol. 2022 Jun 3;5(1):541. doi: 10.1038/s42003-022-03487-6. Commun Biol. 2022. PMID: 35662277 Free PMC article.
Disease-specific iPS cell models in neuroscience.
Peitz M, Jungverdorben J, Brüstle O. Peitz M, et al. Among authors: brustle o. Curr Mol Med. 2013 Jun;13(5):832-41. doi: 10.2174/1566524011313050014. Curr Mol Med. 2013. PMID: 23642064 Review.
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch LJ, Eckert D, Hebisch M, Fischer J, Kesavan J, Weykopf B, Schneider L, Holtkamp D, Beck H, Till A, Wüllner U, Ziller MJ, Wagner W, Peitz M, Brüstle O. Sheng C, et al. Among authors: brustle o. Nat Commun. 2018 Oct 2;9(1):4047. doi: 10.1038/s41467-018-06398-5. Nat Commun. 2018. PMID: 30279449 Free PMC article.
Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models.
Cenini G, Hebisch M, Iefremova V, Flitsch LJ, Breitkreuz Y, Tanzi RE, Kim DY, Peitz M, Brüstle O. Cenini G, et al. Among authors: brustle o. Mol Cell Neurosci. 2021 Jan;110:103568. doi: 10.1016/j.mcn.2020.103568. Epub 2020 Oct 14. Mol Cell Neurosci. 2021. PMID: 33068718 Review.
206 results