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Page 1
Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms.
Jaeger A, Gambheer SMM, Sun X, Chernyakov D, Skorobohatko O, Mack T, Kissel S, Pfeifer D, Zeiser R, Fisch P, Andrieux G, Bräuer-Hartmann D, Bauer M, Schulze S, Follo M, Boerries M, von Bubnoff N, Miething C, Hidalgo JV, Klein C, Weber T, Wickenhauser C, Binder M, Dierks C. Jaeger A, et al. Among authors: brauer hartmann d. Blood. 2023 Jun 8;141(23):2824-2840. doi: 10.1182/blood.2022015653. Blood. 2023. PMID: 36696631
RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia.
Gialesaki S, Bräuer-Hartmann D, Issa H, Bhayadia R, Alejo-Valle O, Verboon L, Schmell AL, Laszig S, Regényi E, Schuschel K, Labuhn M, Ng M, Winkler R, Ihling C, Sinz A, Glaß M, Hüttelmaier S, Matzk S, Schmid L, Strüwe FJ, Kadel SK, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Gialesaki S, et al. Among authors: brauer hartmann d. Blood. 2023 Mar 9;141(10):1105-1118. doi: 10.1182/blood.2022017619. Blood. 2023. PMID: 36493345 Free PMC article.
MicroRNA-143 targets ERK5 in granulopoiesis and predicts outcome of patients with acute myeloid leukemia.
Hartmann JU, Bräuer-Hartmann D, Kardosova M, Wurm AA, Wilke F, Schödel C, Gerloff D, Katzerke C, Krakowsky R, Namasu CY, Bill M, Schwind S, Müller-Tidow C, Niederwieser D, Alberich-Jorda M, Behre G. Hartmann JU, et al. Among authors: brauer hartmann d. Cell Death Dis. 2018 Jul 26;9(8):814. doi: 10.1038/s41419-018-0837-x. Cell Death Dis. 2018. PMID: 30050105 Free PMC article.
miR-451a abrogates treatment resistance in FLT3-ITD-positive acute myeloid leukemia.
Krakowsky RHE, Wurm AA, Gerloff D, Katzerke C, Bräuer-Hartmann D, Hartmann JU, Wilke F, Thiede C, Müller-Tidow C, Niederwieser D, Behre G. Krakowsky RHE, et al. Among authors: brauer hartmann d. Blood Cancer J. 2018 Mar 21;8(3):36. doi: 10.1038/s41408-018-0070-y. Blood Cancer J. 2018. PMID: 29563490 Free PMC article. No abstract available.
ABR, a novel inducer of transcription factor C/EBPα, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia.
Namasu CY, Katzerke C, Bräuer-Hartmann D, Wurm AA, Gerloff D, Hartmann JU, Schwind S, Müller-Tidow C, Hilger N, Fricke S, Christopeit M, Niederwieser D, Behre G. Namasu CY, et al. Among authors: brauer hartmann d. Oncotarget. 2017 Oct 26;8(61):103626-103639. doi: 10.18632/oncotarget.22093. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262589 Free PMC article.
Disruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.
Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Müller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G. Wurm AA, et al. Among authors: brauer hartmann d. Nat Commun. 2017 Jun 29;8(1):46. doi: 10.1038/s41467-017-00032-6. Nat Commun. 2017. PMID: 28663557 Free PMC article.
NF-κB/STAT5/miR-155 network targets PU.1 in FLT3-ITD-driven acute myeloid leukemia.
Gerloff D, Grundler R, Wurm AA, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Madan V, Müller-Tidow C, Duyster J, Tenen DG, Niederwieser D, Behre G. Gerloff D, et al. Among authors: brauer hartmann d. Leukemia. 2015 Mar;29(3):535-47. doi: 10.1038/leu.2014.231. Epub 2014 Aug 5. Leukemia. 2015. PMID: 25092144 Free PMC article.
Transcription factor C/EBPα-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia.
Katzerke C, Madan V, Gerloff D, Bräuer-Hartmann D, Hartmann JU, Wurm AA, Müller-Tidow C, Schnittger S, Tenen DG, Niederwieser D, Behre G. Katzerke C, et al. Among authors: brauer hartmann d. Blood. 2013 Oct 3;122(14):2433-42. doi: 10.1182/blood-2012-12-472183. Epub 2013 Aug 23. Blood. 2013. PMID: 23974200 Free PMC article.