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Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion.
J Vis Exp. 2018 Aug 29;(138):58152. doi: 10.3791/58152.
J Vis Exp. 2018.
PMID: 30222149
Free PMC article.
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
MacLeod G, Bozek DA, Rajakulendran N, Monteiro V, Ahmadi M, Steinhart Z, Kushida MM, Yu H, Coutinho FJ, Cavalli FMG, Restall I, Hao X, Hart T, Luchman HA, Weiss S, Dirks PB, Angers S.
MacLeod G, et al. Among authors: bozek da.
Cell Rep. 2019 Apr 16;27(3):971-986.e9. doi: 10.1016/j.celrep.2019.03.047.
Cell Rep. 2019.
PMID: 30995489
Free article.
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Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.
Richards LM, Whitley OKN, MacLeod G, Cavalli FMG, Coutinho FJ, Jaramillo JE, Svergun N, Riverin M, Croucher DC, Kushida M, Yu K, Guilhamon P, Rastegar N, Ahmadi M, Bhatti JK, Bozek DA, Li N, Lee L, Che C, Luis E, Park NI, Xu Z, Ketela T, Moore RA, Marra MA, Spears J, Cusimano MD, Das S, Bernstein M, Haibe-Kains B, Lupien M, Luchman HA, Weiss S, Angers S, Dirks PB, Bader GD, Pugh TJ.
Richards LM, et al. Among authors: bozek da.
Nat Cancer. 2021 Feb;2(2):157-173. doi: 10.1038/s43018-020-00154-9. Epub 2021 Jan 4.
Nat Cancer. 2021.
PMID: 35122077
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Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics.
Bahia RK, Hao X, Hassam R, Cseh O, Bozek DA, Luchman HA, Weiss S.
Bahia RK, et al. Among authors: bozek da.
Nat Commun. 2023 Aug 19;14(1):5051. doi: 10.1038/s41467-023-40776-y.
Nat Commun. 2023.
PMID: 37598220
Free PMC article.
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BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models.
Hao X, Bahia RK, Cseh O, Bozek DA, Blake S, Rinnenthal J, Weyer-Czernilofsky U, Rudolph D, Artee Luchman H.
Hao X, et al. Among authors: bozek da.
Neuro Oncol. 2023 May 4;25(5):913-926. doi: 10.1093/neuonc/noac271.
Neuro Oncol. 2023.
PMID: 36521007
Free PMC article.
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