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Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade.
Cullen JK, Yap PY, Ferguson B, Bruce ZC, Koyama M, Handoko H, Hendrawan K, Simmons JL, Brooks KM, Johns J, Wilson ES, de Souza MMA, Broit N, Stewart P, Shelley D, McMahon T, Ogbourne SM, Nguyen TH, Lim YC, Pagani A, Appendino G, Gordon VA, Reddell PW, Boyle GM, Parsons PG. Cullen JK, et al. Among authors: boyle gm. J Immunother Cancer. 2024 Apr 24;12(4):e006602. doi: 10.1136/jitc-2022-006602. J Immunother Cancer. 2024. PMID: 38658031 Free PMC article.
First-in-human study of alpibectir (BVL-GSK098), a novel potent anti-TB drug.
Pieren M, Abáigar Gutiérrez-Solana A, Antonijoan Arbós RM, Boyle GW, Davila M, Davy M, Gitzinger M, Husband L, Martínez-Martínez MS, Mazarro DO, Pefani E, Penman SL, Remuiñán MJ, Vlasakakis G, Zeitlinger M, Dale GE. Pieren M, et al. Among authors: boyle gw. J Antimicrob Chemother. 2024 Apr 24:dkae107. doi: 10.1093/jac/dkae107. Online ahead of print. J Antimicrob Chemother. 2024. PMID: 38656557
Pacybara: accurate long-read sequencing for barcoded mutagenized allelic libraries.
Weile J, Ferra G, Boyle G, Pendyala S, Amorosi C, Yeh CL, Cote AG, Kishore N, Tabet D, van Loggerenberg W, Rayhan A, Fowler DM, Dunham MJ, Roth FP. Weile J, et al. Among authors: boyle g. Bioinformatics. 2024 Mar 29;40(4):btae182. doi: 10.1093/bioinformatics/btae182. Bioinformatics. 2024. PMID: 38569896 Free PMC article.
378 results