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Activation of 6-Alkoxy-Substituted Methylenecyclopropane Nucleoside Analogs Requires Enzymatic Modification by Adenosine Deaminase-Like Protein 1.
Vollmer KJ, Burns AC, Sauer HE, Williams JD, Komazin-Meredith G, Cardinale S, Butler M, Aron Z, Hussein I, Busch MG, Bowlin TL, Gentry BG. Vollmer KJ, et al. Among authors: bowlin tl. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01301-19. doi: 10.1128/AAC.01301-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31332074 Free PMC article.
Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.
Prichard MN, Williams JD, Komazin-Meredith G, Khan AR, Price NB, Jefferson GM, Harden EA, Hartline CB, Peet NP, Bowlin TL. Prichard MN, et al. Among authors: bowlin tl. Antimicrob Agents Chemother. 2013 Aug;57(8):3518-27. doi: 10.1128/AAC.00429-13. Epub 2013 May 13. Antimicrob Agents Chemother. 2013. PMID: 23669381 Free PMC article.
Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.
Komazin-Meredith G, Chou S, Prichard MN, Hartline CB, Cardinale SC, Comeau K, Williams JD, Khan AR, Peet NP, Bowlin TL. Komazin-Meredith G, et al. Among authors: bowlin tl. Antimicrob Agents Chemother. 2014;58(1):274-8. doi: 10.1128/AAC.01726-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145545 Free PMC article.
155 results