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Page 1
The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.
Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS. Planas-Paz L, et al. Among authors: bouwmeester t. Nat Cell Biol. 2016 May;18(5):467-79. doi: 10.1038/ncb3337. Epub 2016 Apr 18. Nat Cell Biol. 2016. PMID: 27088858
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F. Hao HX, et al. Among authors: bouwmeester t. Nature. 2012 Apr 29;485(7397):195-200. doi: 10.1038/nature11019. Nature. 2012. PMID: 22575959
Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.
Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS. Planas-Paz L, et al. Among authors: bouwmeester t. Nat Cell Biol. 2016 Oct 27;18(11):1260. doi: 10.1038/ncb3428. Nat Cell Biol. 2016. PMID: 27784900 No abstract available.
YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.
Planas-Paz L, Sun T, Pikiolek M, Cochran NR, Bergling S, Orsini V, Yang Z, Sigoillot F, Jetzer J, Syed M, Neri M, Schuierer S, Morelli L, Hoppe PS, Schwarzer W, Cobos CM, Alford JL, Zhang L, Cuttat R, Waldt A, Carballido-Perrig N, Nigsch F, Kinzel B, Nicholson TB, Yang Y, Mao X, Terracciano LM, Russ C, Reece-Hoyes JS, Gubser Keller C, Sailer AW, Bouwmeester T, Greenbaum LE, Lugus JJ, Cong F, McAllister G, Hoffman GR, Roma G, Tchorz JS. Planas-Paz L, et al. Among authors: bouwmeester t. Cell Stem Cell. 2019 Jul 3;25(1):39-53.e10. doi: 10.1016/j.stem.2019.04.005. Epub 2019 May 9. Cell Stem Cell. 2019. PMID: 31080135 Free article.
AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration.
Sun T, Pikiolek M, Orsini V, Bergling S, Holwerda S, Morelli L, Hoppe PS, Planas-Paz L, Yang Y, Ruffner H, Bouwmeester T, Lohmann F, Terracciano LM, Roma G, Cong F, Tchorz JS. Sun T, et al. Among authors: bouwmeester t. Cell Stem Cell. 2020 Jan 2;26(1):97-107.e6. doi: 10.1016/j.stem.2019.10.011. Epub 2019 Dec 19. Cell Stem Cell. 2020. PMID: 31866224 Free article.
ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation.
Sun T, Annunziato S, Bergling S, Sheng C, Orsini V, Forcella P, Pikiolek M, Kancherla V, Holwerda S, Imanci D, Wu F, Meylan LC, Puehringer LF, Waldt A, Oertli M, Schuierer S, Terracciano LM, Reinker S, Ruffner H, Bouwmeester T, Sailer AW, George E, Roma G, de Weck A, Piscuoglio S, Lohmann F, Naumann U, Liberali P, Cong F, Tchorz JS. Sun T, et al. Among authors: bouwmeester t. Cell Stem Cell. 2021 Oct 7;28(10):1822-1837.e10. doi: 10.1016/j.stem.2021.05.013. Epub 2021 Jun 14. Cell Stem Cell. 2021. PMID: 34129813 Free article.
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, Zietzling S, Beck V, Therier M, Isken A, Xie Y, Zhang Y, Hao H, Shi X, Liu D, Song Q, Clay I, Hintzen G, Tchorz J, Bouchez LC, Michaud G, Finan P, Myer VE, Bouwmeester T, Porter J, Hild M, Bassilana F, Parker CN, Cong F. Ruffner H, et al. Among authors: bouwmeester t. PLoS One. 2012;7(7):e40976. doi: 10.1371/journal.pone.0040976. Epub 2012 Jul 16. PLoS One. 2012. PMID: 22815884 Free PMC article.
Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice.
Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Müller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS. Kinzel B, et al. Among authors: bouwmeester t. Dev Biol. 2014 Jun 15;390(2):181-90. doi: 10.1016/j.ydbio.2014.03.009. Epub 2014 Mar 26. Dev Biol. 2014. PMID: 24680895 Free article.
Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.
Calabrese D, Roma G, Bergling S, Carbone W, Mele V, Nuciforo S, Fofana I, Campana B, Szkolnicka D, Hay DC, Tchorz J, Bouwmeester T, Wieland S, Heim MH. Calabrese D, et al. Among authors: bouwmeester t. PLoS One. 2019 Aug 29;14(8):e0221762. doi: 10.1371/journal.pone.0221762. eCollection 2019. PLoS One. 2019. PMID: 31465481 Free PMC article.
YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.
Marti P, Stein C, Blumer T, Abraham Y, Dill MT, Pikiolek M, Orsini V, Jurisic G, Megel P, Makowska Z, Agarinis C, Tornillo L, Bouwmeester T, Ruffner H, Bauer A, Parker CN, Schmelzle T, Terracciano LM, Heim MH, Tchorz JS. Marti P, et al. Among authors: bouwmeester t. Hepatology. 2015 Nov;62(5):1497-510. doi: 10.1002/hep.27992. Epub 2015 Aug 25. Hepatology. 2015. PMID: 26173433
99 results