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USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Kassel S, et al. Among authors: boutros m. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749823 Free PMC article.
Wnt signaling signaling at and above the receptor level.
Buechling T, Boutros M. Buechling T, et al. Among authors: boutros m. Curr Top Dev Biol. 2011;97:21-53. doi: 10.1016/B978-0-12-385975-4.00008-5. Curr Top Dev Biol. 2011. PMID: 22074601 Review.
p24 proteins are required for secretion of Wnt ligands.
Buechling T, Chaudhary V, Spirohn K, Weiss M, Boutros M. Buechling T, et al. Among authors: boutros m. EMBO Rep. 2011 Dec 1;12(12):1265-72. doi: 10.1038/embor.2011.212. EMBO Rep. 2011. PMID: 22094269 Free PMC article.
Active Wnt proteins are secreted on exosomes.
Gross JC, Chaudhary V, Bartscherer K, Boutros M. Gross JC, et al. Among authors: boutros m. Nat Cell Biol. 2012 Oct;14(10):1036-45. doi: 10.1038/ncb2574. Epub 2012 Sep 16. Nat Cell Biol. 2012. PMID: 22983114
Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling.
Serysheva E, Berhane H, Grumolato L, Demir K, Balmer S, Bodak M, Boutros M, Aaronson S, Mlodzik M, Jenny A. Serysheva E, et al. Among authors: boutros m. EMBO Rep. 2013 Aug;14(8):718-25. doi: 10.1038/embor.2013.88. Epub 2013 Jun 25. EMBO Rep. 2013. PMID: 23797875 Free PMC article.
Wnt signaling in cancer.
Zhan T, Rindtorff N, Boutros M. Zhan T, et al. Among authors: boutros m. Oncogene. 2017 Mar;36(11):1461-1473. doi: 10.1038/onc.2016.304. Epub 2016 Sep 12. Oncogene. 2017. PMID: 27617575 Free PMC article. Review.
384 results