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Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.
Voloshanenko O, Erdmann G, Dubash TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Kerr G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M. Voloshanenko O, et al. Among authors: boutros m. Nat Commun. 2013;4:2610. doi: 10.1038/ncomms3610. Nat Commun. 2013. PMID: 24162018 Free PMC article.
Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.
Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus HA, Berriel Diaz M, Backs J, Herzig S. Schäfer M, et al. Among authors: boutros m. Mol Metab. 2015 Nov 26;5(2):67-78. doi: 10.1016/j.molmet.2015.11.004. eCollection 2016 Feb. Mol Metab. 2015. PMID: 26909315 Free PMC article.
Refining Pathways: A Model Comparison Approach.
Moffa G, Erdmann G, Voloshanenko O, Hundsrucker C, Sadeh MJ, Boutros M, Spang R. Moffa G, et al. Among authors: boutros m. PLoS One. 2016 Jun 1;11(6):e0155999. doi: 10.1371/journal.pone.0155999. eCollection 2016. PLoS One. 2016. PMID: 27248690 Free PMC article.
Biochemical Methods to Analyze Wnt Protein Secretion.
Glaeser K, Boutros M, Gross JC. Glaeser K, et al. Among authors: boutros m. Methods Mol Biol. 2016;1481:17-28. doi: 10.1007/978-1-4939-6393-5_3. Methods Mol Biol. 2016. PMID: 27590148
Wnt signaling in cancer.
Zhan T, Rindtorff N, Boutros M. Zhan T, et al. Among authors: boutros m. Oncogene. 2017 Mar;36(11):1461-1473. doi: 10.1038/onc.2016.304. Epub 2016 Sep 12. Oncogene. 2017. PMID: 27617575 Free PMC article. Review.
Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.
Voloshanenko O, Gmach P, Winter J, Kranz D, Boutros M. Voloshanenko O, et al. Among authors: boutros m. FASEB J. 2017 Nov;31(11):4832-4844. doi: 10.1096/fj.201700144R. Epub 2017 Jul 21. FASEB J. 2017. PMID: 28733458 Free PMC article.
Together, our results map functional interactions of FZDs and 10 Wnt ligands and demonstrate how multiplex targeting by clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 can be used to systematically elucidate the functions of multigene families.-Voloshanenko …
Together, our results map functional interactions of FZDs and 10 Wnt ligands and demonstrate how multiplex targeting by clustered regularly …
ERAD-dependent control of the Wnt secretory factor Evi.
Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, Christianson JC, Boutros M. Glaeser K, et al. Among authors: boutros m. EMBO J. 2018 Feb 15;37(4):e97311. doi: 10.15252/embj.201797311. Epub 2018 Jan 29. EMBO J. 2018. PMID: 29378775 Free PMC article.
384 results