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SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function.
Bouti P, Klein BJAM, Verkuijlen PJH, Schornagel K, van Alphen FPJ, Taris KH, van den Biggelaar M, Hoogendijk AJ, van Bruggen R, Kuijpers TW, Matlung HL. Bouti P, et al. Front Immunol. 2024 Feb 29;15:1344761. doi: 10.3389/fimmu.2024.1344761. eCollection 2024. Front Immunol. 2024. PMID: 38487529 Free PMC article.
Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex.
van Rees DJ, Bouti P, Klein B, Verkuijlen PJH, van Houdt M, Schornagel K, Tool ATJ, Venet D, Sotiriou C, El-Abed S, Izquierdo M, Guillaume S, Saura C, Di Cosimo S, Huober J, Roylance R, Kim SB, Kuijpers TW, van Bruggen R, van den Berg TK, Matlung HL. van Rees DJ, et al. Among authors: bouti p. J Immunother Cancer. 2022 Jun;10(6):e004820. doi: 10.1136/jitc-2022-004820. J Immunother Cancer. 2022. PMID: 35728876 Free PMC article.
G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment.
Martinez Sanz P, van Rees DJ, van Zogchel LMJ, Klein B, Bouti P, Olsman H, Schornagel K, Kok I, Sunak A, Leeuwenburg K, Timmerman I, Dierselhuis MP, Kholosy WM, Molenaar JJ, van Bruggen R, van den Berg TK, Kuijpers TW, Matlung HL, Tytgat GAM, Franke K. Martinez Sanz P, et al. Among authors: bouti p. J Immunother Cancer. 2021 May;9(5):e002259. doi: 10.1136/jitc-2020-002259. J Immunother Cancer. 2021. PMID: 34049929 Free PMC article.