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Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an In Vivo Efficacious TLR7/8 Antagonist.
Betschart C, Faller M, Zink F, Hemmig R, Blank J, Vangrevelinghe E, Bourrel M, Glatthar R, Behnke D, Barker K, Heizmann A, Angst D, Nimsgern P, Jacquier S, Junt T, Zipfel G, Ruzzante G, Loetscher P, Limonta S, Hawtin S, Andre CB, Boulay T, Feifel R, Knoepfel T. Betschart C, et al. Among authors: bourrel m. ACS Med Chem Lett. 2022 Mar 10;13(4):658-664. doi: 10.1021/acsmedchemlett.1c00696. eCollection 2022 Apr 14. ACS Med Chem Lett. 2022. PMID: 35450354 Free PMC article.
Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay.
Knoepfel T, Nimsgern P, Jacquier S, Bourrel M, Vangrevelinghe E, Glatthar R, Behnke D, Alper PB, Michellys PY, Deane J, Junt T, Zipfel G, Limonta S, Hawtin S, Andre C, Boulay T, Loetscher P, Faller M, Blank J, Feifel R, Betschart C. Knoepfel T, et al. Among authors: bourrel m. J Med Chem. 2020 Aug 13;63(15):8276-8295. doi: 10.1021/acs.jmedchem.0c00130. Epub 2020 Jul 30. J Med Chem. 2020. PMID: 32786235
[Let's talk about love].
Bourrel MC. Bourrel MC. Soins Psychiatr. 2004 Jul-Aug;(233):16-20. Soins Psychiatr. 2004. PMID: 15339099 Review. French. No abstract available.
[Naevus spilus].
Bourrel M. Bourrel M. Ann Dermatol Venereol. 2004 Feb;131(2):225. doi: 10.1016/s0151-9638(04)93582-x. Ann Dermatol Venereol. 2004. PMID: 15061131 French. No abstract available.
[Cardiovascular disorders in the antabuse-alcohol reaction].
FABREGOULE M, POROT M, DUBOUCHER G, BOURREL M. FABREGOULE M, et al. Among authors: bourrel m. Alger Medicale. 1950 May;54(5):237-8. Alger Medicale. 1950. PMID: 15432260 Undetermined Language. No abstract available.
15 results