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Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.
Arsic N, Slatter T, Gadea G, Villain E, Fournet A, Kazantseva M, Allemand F, Sibille N, Seveno M, de Rossi S, Mehta S, Urbach S, Bourdon JC, Bernado P, Kajava AV, Braithwaite A, Roux P. Arsic N, et al. Among authors: bourdon jc. Nat Commun. 2021 Sep 15;12(1):5463. doi: 10.1038/s41467-021-25550-2. Nat Commun. 2021. PMID: 34526502 Free PMC article.
Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript.
Marcel V, Perrier S, Aoubala M, Ageorges S, Groves MJ, Diot A, Fernandes K, Tauro S, Bourdon JC. Marcel V, et al. Among authors: bourdon jc. FEBS Lett. 2010 Nov 5;584(21):4463-8. doi: 10.1016/j.febslet.2010.10.005. Epub 2010 Oct 13. FEBS Lett. 2010. PMID: 20937277 Free article.
The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.
Bernard H, Garmy-Susini B, Ainaoui N, Van Den Berghe L, Peurichard A, Javerzat S, Bikfalvi A, Lane DP, Bourdon JC, Prats AC. Bernard H, et al. Among authors: bourdon jc. Oncogene. 2013 Apr 25;32(17):2150-60. doi: 10.1038/onc.2012.242. Epub 2012 Jun 25. Oncogene. 2013. PMID: 22733133 Free article.
TP53 drives invasion through expression of its Δ133p53β variant.
Gadea G, Arsic N, Fernandes K, Diot A, Joruiz SM, Abdallah S, Meuray V, Vinot S, Anguille C, Remenyi J, Khoury MP, Quinlan PR, Purdie CA, Jordan LB, Fuller-Pace FV, de Toledo M, Cren M, Thompson AM, Bourdon JC, Roux P. Gadea G, et al. Among authors: bourdon jc. Elife. 2016 Sep 15;5:e14734. doi: 10.7554/eLife.14734. Elife. 2016. PMID: 27630122 Free PMC article.
Adaptive homeostasis and the p53 isoform network.
Mehta S, Campbell H, Drummond CJ, Li K, Murray K, Slatter T, Bourdon JC, Braithwaite AW. Mehta S, et al. Among authors: bourdon jc. EMBO Rep. 2021 Dec 6;22(12):e53085. doi: 10.15252/embr.202153085. Epub 2021 Nov 15. EMBO Rep. 2021. PMID: 34779563 Free PMC article. Review.
p53 isoforms can regulate p53 transcriptional activity.
Bourdon JC, Fernandes K, Murray-Zmijewski F, Liu G, Diot A, Xirodimas DP, Saville MK, Lane DP. Bourdon JC, et al. Genes Dev. 2005 Sep 15;19(18):2122-37. doi: 10.1101/gad.1339905. Epub 2005 Aug 30. Genes Dev. 2005. PMID: 16131611 Free PMC article.
p53 Family isoforms.
Bourdon JC. Bourdon JC. Curr Pharm Biotechnol. 2007 Dec;8(6):332-6. doi: 10.2174/138920107783018444. Curr Pharm Biotechnol. 2007. PMID: 18289041 Free PMC article. Review.
95 results