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Page 1
TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients.
Caceres G, McGraw K, Yip BH, Pellagatti A, Johnson J, Zhang L, Liu K, Zhang LM, Fulp WJ, Lee JH, Al Ali NH, Basiorka A, Smith LJ, Daugherty FJ, Littleton N, Wells RA, Sokol L, Wei S, Komrokji RS, Boultwood J, List AF. Caceres G, et al. Among authors: boultwood j. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16127-32. doi: 10.1073/pnas.1311055110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043769 Free PMC article.
Gene expression profiling in the myelodysplastic syndromes.
Pellagatti A, Fidler C, Wainscoat JS, Boultwood J. Pellagatti A, et al. Among authors: boultwood j. Hematology. 2005 Aug;10(4):281-7. doi: 10.1080/10245330500065680. Hematology. 2005. PMID: 16085540 Review.
Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.
Pellagatti A, Cazzola M, Giagounidis AA, Malcovati L, Porta MG, Killick S, Campbell LJ, Wang L, Langford CF, Fidler C, Oscier D, Aul C, Wainscoat JS, Boultwood J. Pellagatti A, et al. Among authors: boultwood j. Blood. 2006 Jul 1;108(1):337-45. doi: 10.1182/blood-2005-12-4769. Epub 2006 Mar 9. Blood. 2006. PMID: 16527891 Free article.
Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
Pellagatti A, Jädersten M, Forsblom AM, Cattan H, Christensson B, Emanuelsson EK, Merup M, Nilsson L, Samuelsson J, Sander B, Wainscoat JS, Boultwood J, Hellström-Lindberg E. Pellagatti A, et al. Among authors: boultwood j. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11406-11. doi: 10.1073/pnas.0610477104. Epub 2007 Jun 18. Proc Natl Acad Sci U S A. 2007. PMID: 17576924 Free PMC article.
Gene expression profiling of CD34+ cells in patients with the 5q- syndrome.
Boultwood J, Pellagatti A, Cattan H, Lawrie CH, Giagounidis A, Malcovati L, Della Porta MG, Jädersten M, Killick S, Fidler C, Cazzola M, Hellström-Lindberg E, Wainscoat JS. Boultwood J, et al. Br J Haematol. 2007 Nov;139(4):578-89. doi: 10.1111/j.1365-2141.2007.06833.x. Epub 2007 Oct 3. Br J Haematol. 2007. PMID: 17916100 Free article.
Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.
Zhou L, Nguyen AN, Sohal D, Ying Ma J, Pahanish P, Gundabolu K, Hayman J, Chubak A, Mo Y, Bhagat TD, Das B, Kapoun AM, Navas TA, Parmar S, Kambhampati S, Pellagatti A, Braunchweig I, Zhang Y, Wickrema A, Medicherla S, Boultwood J, Platanias LC, Higgins LS, List AF, Bitzer M, Verma A. Zhou L, et al. Among authors: boultwood j. Blood. 2008 Oct 15;112(8):3434-43. doi: 10.1182/blood-2008-02-139824. Epub 2008 May 12. Blood. 2008. PMID: 18474728 Free PMC article.
Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
Jädersten M, Saft L, Pellagatti A, Göhring G, Wainscoat JS, Boultwood J, Porwit A, Schlegelberger B, Hellström-Lindberg E. Jädersten M, et al. Among authors: boultwood j. Haematologica. 2009 Dec;94(12):1762-6. doi: 10.3324/haematol.2009.011528. Epub 2009 Oct 1. Haematologica. 2009. PMID: 19797731 Free PMC article.
Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome.
Pellagatti A, Marafioti T, Paterson JC, Barlow JL, Drynan LF, Giagounidis A, Pileri SA, Cazzola M, McKenzie AN, Wainscoat JS, Boultwood J. Pellagatti A, et al. Among authors: boultwood j. Blood. 2010 Apr 1;115(13):2721-3. doi: 10.1182/blood-2009-12-259705. Blood. 2010. PMID: 20360478 Free article. No abstract available.
Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF.
Nikpour M, Pellagatti A, Liu A, Karimi M, Malcovati L, Gogvadze V, Forsblom AM, Wainscoat JS, Cazzola M, Zhivotovsky B, Grandien A, Boultwood J, Hellström-Lindberg E. Nikpour M, et al. Among authors: boultwood j. Br J Haematol. 2010 Jun;149(6):844-54. doi: 10.1111/j.1365-2141.2010.08174.x. Epub 2010 Apr 12. Br J Haematol. 2010. PMID: 20408843 Free article.
Advances in the 5q- syndrome.
Boultwood J, Pellagatti A, McKenzie AN, Wainscoat JS. Boultwood J, et al. Blood. 2010 Dec 23;116(26):5803-11. doi: 10.1182/blood-2010-04-273771. Epub 2010 Aug 23. Blood. 2010. PMID: 20733155 Free article. Review.
241 results