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Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu WT, Dietzen M, Galanos P, Evangelou K, Bellelli R, Lim EL, Watkins TBK, Rowan A, Teixeira VH, Zhao Y, Chen H, Ngo B, Zalmas LP, Al Bakir M, Hobor S, Grönroos E, Pennycuick A, Nigro E, Campbell BB, Brown WL, Akarca AU, Marafioti T, Wu MY, Howell M, Boulton SJ, Bertoli C, Fenton TR, de Bruin RAM, Maya-Mendoza A, Santoni-Rugiu E, Hynds RE, Gorgoulis VG, Jamal-Hanjani M, McGranahan N, Harris RS, Janes SM, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C; TRACERx Consortium. Venkatesan S, et al. Among authors: boulton sj. Cancer Discov. 2021 Oct;11(10):2456-2473. doi: 10.1158/2159-8290.CD-20-0725. Epub 2021 May 4. Cancer Discov. 2021. PMID: 33947663 Free PMC article.
The centriolar satellite protein Cep131 is important for genome stability.
Staples CJ, Myers KN, Beveridge RD, Patil AA, Lee AJ, Swanton C, Howell M, Boulton SJ, Collis SJ. Staples CJ, et al. Among authors: boulton sj. J Cell Sci. 2012 Oct 15;125(Pt 20):4770-9. doi: 10.1242/jcs.104059. Epub 2012 Jul 13. J Cell Sci. 2012. PMID: 22797915
Mechanisms of DNA-protein crosslink repair.
Stingele J, Bellelli R, Boulton SJ. Stingele J, et al. Among authors: boulton sj. Nat Rev Mol Cell Biol. 2017 Sep;18(9):563-573. doi: 10.1038/nrm.2017.56. Epub 2017 Jun 28. Nat Rev Mol Cell Biol. 2017. PMID: 28655905 Review.
Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis.
Bellelli R, Borel V, Logan C, Svendsen J, Cox DE, Nye E, Metcalfe K, O'Connell SM, Stamp G, Flynn HR, Snijders AP, Lassailly F, Jackson A, Boulton SJ. Bellelli R, et al. Among authors: boulton sj. Mol Cell. 2018 May 17;70(4):707-721.e7. doi: 10.1016/j.molcel.2018.04.008. Epub 2018 May 10. Mol Cell. 2018. PMID: 29754823 Free PMC article.
163 results