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RTEL-1 enforces meiotic crossover interference and homeostasis.
Youds JL, Mets DG, McIlwraith MJ, Martin JS, Ward JD, ONeil NJ, Rose AM, West SC, Meyer BJ, Boulton SJ. Youds JL, et al. Among authors: boulton sj. Science. 2010 Mar 5;327(5970):1254-8. doi: 10.1126/science.1183112. Science. 2010. PMID: 20203049 Free PMC article.
Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1.
Lehmann LC, Hewitt G, Aibara S, Leitner A, Marklund E, Maslen SL, Maturi V, Chen Y, van der Spoel D, Skehel JM, Moustakas A, Boulton SJ, Deindl S. Lehmann LC, et al. Among authors: boulton sj. Mol Cell. 2017 Dec 7;68(5):847-859.e7. doi: 10.1016/j.molcel.2017.10.017. Mol Cell. 2017. PMID: 29220652 Free PMC article.
Beyond PARP-POLθ as an anticancer target.
Higgins GS, Boulton SJ. Higgins GS, et al. Among authors: boulton sj. Science. 2018 Mar 16;359(6381):1217-1218. doi: 10.1126/science.aar5149. Science. 2018. PMID: 29590065 No abstract available.
SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.
Panier S, Maric M, Hewitt G, Mason-Osann E, Gali H, Dai A, Labadorf A, Guervilly JH, Ruis P, Segura-Bayona S, Belan O, Marzec P, Gaillard PL, Flynn RL, Boulton SJ. Panier S, et al. Among authors: boulton sj. Mol Cell. 2019 Oct 3;76(1):27-43.e11. doi: 10.1016/j.molcel.2019.07.010. Epub 2019 Aug 22. Mol Cell. 2019. PMID: 31447390 Free PMC article.
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Hewitt G, et al. Among authors: boulton sj. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333017 Free PMC article.
163 results