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Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2.
Guragossian N, Belhani B, Moreno A, Nunes MT, Gonzalez-Lobato L, Marminon C, Berthier L, Rocio Andrade Pires AD, Özvegy-Laczka C, Sarkadi B, Terreux R, Bouaziz Z, Berredjem M, Jose J, Di Pietro A, Falson P, Le Borgne M. Guragossian N, et al. Among authors: bouaziz z. Eur J Med Chem. 2021 Feb 5;211:113017. doi: 10.1016/j.ejmech.2020.113017. Epub 2020 Nov 12. Eur J Med Chem. 2021. PMID: 33223263
Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2.
Jabor Gozzi G, Bouaziz Z, Winter E, Daflon-Yunes N, Aichele D, Nacereddine A, Marminon C, Valdameri G, Zeinyeh W, Bollacke A, Guillon J, Lacoudre A, Pinaud N, Cadena SM, Jose J, Le Borgne M, Di Pietro A. Jabor Gozzi G, et al. Among authors: bouaziz z. J Med Chem. 2015 Jan 8;58(1):265-77. doi: 10.1021/jm500943z. Epub 2014 Oct 16. J Med Chem. 2015. PMID: 25272055
Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity.
Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Guragossian N, Marminon C, Valdameri G, Bollacke A, Guillon J, Pinaud N, Marchivie M, Cadena SM, Jose J, Le Borgne M, Di Pietro A. Gozzi GJ, et al. Among authors: bouaziz z. Drug Des Devel Ther. 2015 Jul 3;9:3481-95. doi: 10.2147/DDDT.S84982. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26170632 Free PMC article.
Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles.
Kita DH, Guragossian N, Zattoni IF, Moure VR, Rego FGM, Lusvarghi S, Moulenat T, Belhani B, Picheth G, Bouacida S, Bouaziz Z, Marminon C, Berredjem M, Jose J, Gonçalves MB, Ambudkar SV, Valdameri G, Le Borgne M. Kita DH, et al. Among authors: bouaziz z. Sci Rep. 2021 Jan 19;11(1):1788. doi: 10.1038/s41598-020-79892-w. Sci Rep. 2021. PMID: 33469044 Free PMC article.
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion.
Bouzina A, Berredjem M, Nocentini A, Bua S, Bouaziz Z, Jose J, Le Borgne M, Marminon C, Gratteri P, Supuran CT. Bouzina A, et al. Among authors: bouaziz z. Eur J Med Chem. 2021 Jan 1;209:112875. doi: 10.1016/j.ejmech.2020.112875. Epub 2020 Oct 5. Eur J Med Chem. 2021. PMID: 33059188
Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds.
Bouaziz Z, Issa S, Gentili J, Gratz A, Bollacke A, Kassack M, Jose J, Herfindal L, Gausdal G, Døskeland SO, Mullié C, Sonnet P, Desgrouas C, Taudon N, Valdameri G, Di Pietro A, Baitiche M, Le Borgne M. Bouaziz Z, et al. J Enzyme Inhib Med Chem. 2015 Apr;30(2):180-8. doi: 10.3109/14756366.2014.899594. Epub 2014 Apr 3. J Enzyme Inhib Med Chem. 2015. PMID: 24697298
47 results