Botting C - Search Results

1

Structural analysis of leader peptide binding enables leader-free cyanobactin processing.

Koehnke J, Mann G, Bent AF, Ludewig H, Shirran S, Botting C, Lebl T, Houssen W, Jaspars M, Naismith JH. Koehnke J, et al. Among authors: botting c. Nat Chem Biol. 2015 Aug;11(8):558-563. doi: 10.1038/nchembio.1841. Epub 2015 Jun 22. Nat Chem Biol. 2015. PMID: 26098679 Free PMC article.

2

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain.

Koehnke J, Bent A, Houssen WE, Zollman D, Morawitz F, Shirran S, Vendome J, Nneoyiegbe AF, Trembleau L, Botting CH, Smith MC, Jaspars M, Naismith JH. Koehnke J, et al. Among authors: botting ch. Nat Struct Mol Biol. 2012 Aug;19(8):767-72. doi: 10.1038/nsmb.2340. Epub 2012 Jul 15. Nat Struct Mol Biol. 2012. PMID: 22796963 Free PMC article.

3

An enzymatic route to selenazolines.

Koehnke J, Morawitz F, Bent AF, Houssen WE, Shirran SL, Fuszard MA, Smellie IA, Botting CH, Smith MC, Jaspars M, Naismith JH. Koehnke J, et al. Among authors: botting ch. Chembiochem. 2013 Mar 18;14(5):564-7. doi: 10.1002/cbic.201300037. Epub 2013 Feb 18. Chembiochem. 2013. PMID: 23483642 Free PMC article.

4

AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis.

Schmelz S, Kadi N, McMahon SA, Song L, Oves-Costales D, Oke M, Liu H, Johnson KA, Carter LG, Botting CH, White MF, Challis GL, Naismith JH. Schmelz S, et al. Nat Chem Biol. 2009 Mar;5(3):174-82. doi: 10.1038/nchembio.145. Epub 2009 Feb 1. Nat Chem Biol. 2009. PMID: 19182782 Free PMC article.

5

Insights into the biosynthesis of the Vibrio cholerae major autoinducer CAI-1 from the crystal structure of the PLP-dependent enzyme CqsA.

Jahan N, Potter JA, Sheikh MA, Botting CH, Shirran SL, Westwood NJ, Taylor GL. Jahan N, et al. J Mol Biol. 2009 Sep 25;392(3):763-73. doi: 10.1016/j.jmb.2009.07.042. Epub 2009 Jul 22. J Mol Biol. 2009. PMID: 19631226

6

Structural basis for acyl acceptor specificity in the achromobactin biosynthetic enzyme AcsD.

Schmelz S, Botting CH, Song L, Kadi NF, Challis GL, Naismith JH. Schmelz S, et al. J Mol Biol. 2011 Sep 23;412(3):495-504. doi: 10.1016/j.jmb.2011.07.059. Epub 2011 Aug 1. J Mol Biol. 2011. PMID: 21835184 Free PMC article.

7

The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction.

Koehnke J, Bent AF, Zollman D, Smith K, Houssen WE, Zhu X, Mann G, Lebl T, Scharff R, Shirran S, Botting CH, Jaspars M, Schwarz-Linek U, Naismith JH. Koehnke J, et al. Angew Chem Int Ed Engl. 2013 Dec 23;52(52):13991-6. doi: 10.1002/anie.201306302. Epub 2013 Nov 8. Angew Chem Int Ed Engl. 2013. PMID: 24214017 Free PMC article. No abstract available.

8

Insights into the Mechanism of the Cyanobactin Heterocyclase Enzyme.

Ge Y, Czekster CM, Miller OK, Botting CH, Schwarz-Linek U, Naismith JH. Ge Y, et al. Among authors: botting ch. Biochemistry. 2019 Apr 23;58(16):2125-2132. doi: 10.1021/acs.biochem.9b00084. Epub 2019 Apr 5. Biochemistry. 2019. PMID: 30912640 Free PMC article.

9

Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule.

Yang J, Wang Y, Wang T, Jiang J, Botting CH, Liu H, Chen Q, Yang J, Naismith JH, Zhu X, Chen L. Yang J, et al. Nat Commun. 2016 Jun 30;7:12103. doi: 10.1038/ncomms12103. Nat Commun. 2016. PMID: 27357539 Free PMC article.

10

A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods.

Shirran SL, Botting CH. Shirran SL, et al. J Proteomics. 2010 May 7;73(7):1391-403. doi: 10.1016/j.jprot.2010.03.003. Epub 2010 Mar 15. J Proteomics. 2010. PMID: 20230925 Free PMC article.

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