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RIPK4 regulates cell-cell adhesion in epidermal development and homeostasis.
Fortugno P, Monetta R, Belli M, Botti E, Angelucci F, Palmerini MG, Nottola SA, De Luca C, Ceccarini M, Salvatore M, Bianchi L, Macioce P, Teson M, Ricci F; Italian Undiagnosed Diseases Network; Macchiarelli G, Didona B, Costanzo A, Castiglia D, Brancati F. Fortugno P, et al. Among authors: botti e. Hum Mol Genet. 2022 Aug 17;31(15):2535-2547. doi: 10.1093/hmg/ddac046. Hum Mol Genet. 2022. PMID: 35220430
The tumor suppressor activity of IKKalpha in stratified epithelia is exerted in part via the TGF-beta antiproliferative pathway.
Marinari B, Moretti F, Botti E, Giustizieri ML, Descargues P, Giunta A, Stolfi C, Ballaro C, Papoutsaki M, Alemà S, Monteleone G, Chimenti S, Karin M, Costanzo A. Marinari B, et al. Among authors: botti e. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17091-6. doi: 10.1073/pnas.0809288105. Epub 2008 Oct 28. Proc Natl Acad Sci U S A. 2008. PMID: 18957551 Free PMC article.
Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis.
Caruso R, Botti E, Sarra M, Esposito M, Stolfi C, Diluvio L, Giustizieri ML, Pacciani V, Mazzotta A, Campione E, Macdonald TT, Chimenti S, Pallone F, Costanzo A, Monteleone G. Caruso R, et al. Among authors: botti e. Nat Med. 2009 Sep;15(9):1013-5. doi: 10.1038/nm.1995. Epub 2009 Aug 16. Nat Med. 2009. PMID: 19684581
A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias.
Moretti F, Marinari B, Lo Iacono N, Botti E, Giunta A, Spallone G, Garaffo G, Vernersson-Lindahl E, Merlo G, Mills AA, Ballarò C, Alemà S, Chimenti S, Guerrini L, Costanzo A. Moretti F, et al. Among authors: botti e. J Clin Invest. 2010 May;120(5):1570-7. doi: 10.1172/JCI40267. Epub 2010 Apr 26. J Clin Invest. 2010. PMID: 20424325 Free PMC article.
IL-21 in the pathogenesis and treatment of skin diseases.
Costanzo A, Chimenti MS, Botti E, Caruso R, Sarra M, Monteleone G. Costanzo A, et al. Among authors: botti e. J Dermatol Sci. 2010 Nov;60(2):61-6. doi: 10.1016/j.jdermsci.2010.08.016. Epub 2010 Sep 15. J Dermatol Sci. 2010. PMID: 20888735 Review.
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
Botti E, Spallone G, Moretti F, Marinari B, Pinetti V, Galanti S, De Meo PD, De Nicola F, Ganci F, Castrignanò T, Pesole G, Chimenti S, Guerrini L, Fanciulli M, Blandino G, Karin M, Costanzo A. Botti E, et al. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13710-5. doi: 10.1073/pnas.1110931108. Epub 2011 Aug 1. Proc Natl Acad Sci U S A. 2011. PMID: 21807998 Free PMC article.
Targeted therapy in nonmelanoma skin cancers.
Spallone G, Botti E, Costanzo A. Spallone G, et al. Among authors: botti e. Cancers (Basel). 2011 May 3;3(2):2255-73. doi: 10.3390/cancers3022255. Cancers (Basel). 2011. PMID: 24212808 Free PMC article.
78 results