Botelho HM - Search Results

1

Searching for a Paradigm Shift in Auger-Electron Cancer Therapy with Tumor-Specific Radiopeptides Targeting the Mitochondria and/or the Cell Nucleus.

Fernandes C, Palma E, Silva F, Belchior A, Pinto CIG, Guerreiro JF, Botelho HM, Mendes F, Raposinho P, Paulo A. Fernandes C, et al. Among authors: botelho hm. Int J Mol Sci. 2022 Jun 29;23(13):7238. doi: 10.3390/ijms23137238. Int J Mol Sci. 2022. PMID: 35806239 Free PMC article.

2

Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies.

Palma E, Botelho HM, Morais GR, Rodrigues I, Santos IC, Campello MPC, Raposinho P, Belchior A, Gomes SS, Araújo MF, Correia I, Ribeiro N, Gama S, Mendes F, Paulo A. Palma E, et al. Among authors: botelho hm. J Biol Inorg Chem. 2019 Feb;24(1):71-89. doi: 10.1007/s00775-018-1629-6. Epub 2018 Nov 24. J Biol Inorg Chem. 2019. PMID: 30474755

3

Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions.

Uliyakina I, Botelho HM, da Paula AC, Afonso S, Lobo MJ, Felício V, Farinha CM, Amaral MD. Uliyakina I, et al. Among authors: botelho hm. Int J Mol Sci. 2020 Jun 25;21(12):4524. doi: 10.3390/ijms21124524. Int J Mol Sci. 2020. PMID: 32630527 Free PMC article.

4

Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery.

Botelho HM, Uliyakina I, Awatade NT, Proença MC, Tischer C, Sirianant L, Kunzelmann K, Pepperkok R, Amaral MD. Botelho HM, et al. Sci Rep. 2015 Mar 12;5:9038. doi: 10.1038/srep09038. Sci Rep. 2015. PMID: 25762484 Free PMC article.

5

Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators.

Clarke LA, Botelho HM, Sousa L, Falcao AO, Amaral MD. Clarke LA, et al. Among authors: botelho hm. Genomics. 2015 Nov;106(5):268-77. doi: 10.1016/j.ygeno.2015.07.005. Epub 2015 Jul 29. Genomics. 2015. PMID: 26225835 Free article.

6

Correction of a Cystic Fibrosis Splicing Mutation by Antisense Oligonucleotides.

Igreja S, Clarke LA, Botelho HM, Marques L, Amaral MD. Igreja S, et al. Among authors: botelho hm. Hum Mutat. 2016 Feb;37(2):209-15. doi: 10.1002/humu.22931. Epub 2015 Dec 2. Hum Mutat. 2016. PMID: 26553470

7

Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Amaral MD, Farinha CM, Matos P, Botelho HM. Amaral MD, et al. Among authors: botelho hm. Methods Mol Biol. 2016;1459:105-26. doi: 10.1007/978-1-4939-3804-9_7. Methods Mol Biol. 2016. PMID: 27665554

8

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic.

Lérias JR, Pinto MC, Botelho HM, Awatade NT, Quaresma MC, Silva IAL, Wanitchakool P, Schreiber R, Pepperkok R, Kunzelmann K, Amaral MD. Lérias JR, et al. Among authors: botelho hm. Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):421-431. doi: 10.1016/j.bbamcr.2017.11.009. Epub 2017 Nov 15. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 29154949 Free article.

9

R560S: A class II CFTR mutation that is not rescued by current modulators.

Awatade NT, Ramalho S, Silva IAL, Felício V, Botelho HM, de Poel E, Vonk A, Beekman JM, Farinha CM, Amaral MD. Awatade NT, et al. Among authors: botelho hm. J Cyst Fibros. 2019 Mar;18(2):182-189. doi: 10.1016/j.jcf.2018.07.001. Epub 2018 Jul 18. J Cyst Fibros. 2019. PMID: 30030066 Free article.

10

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum.

Santos JD, Canato S, Carvalho AS, Botelho HM, Aloria K, Amaral MD, Matthiesen R, Falcao AO, Farinha CM. Santos JD, et al. Among authors: botelho hm. Cells. 2019 Apr 14;8(4):353. doi: 10.3390/cells8040353. Cells. 2019. PMID: 31014000 Free PMC article.

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