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Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart.
van der Velden J, Asselbergs FW, Bakkers J, Batkai S, Bertrand L, Bezzina CR, Bot I, Brundel BJJM, Carrier L, Chamuleau S, Ciccarelli M, Dawson D, Davidson SM, Dendorfer A, Duncker DJ, Eschenhagen T, Fabritz L, Falcão-Pires I, Ferdinandy P, Giacca M, Girao H, Gollmann-Tepeköylü C, Gyongyosi M, Guzik TJ, Hamdani N, Heymans S, Hilfiker A, Hilfiker-Kleiner D, Hoekstra AG, Hulot JS, Kuster DWD, van Laake LW, Lecour S, Leiner T, Linke WA, Lumens J, Lutgens E, Madonna R, Maegdefessel L, Mayr M, van der Meer P, Passier R, Perbellini F, Perrino C, Pesce M, Priori S, Remme CA, Rosenhahn B, Schotten U, Schulz R, Sipido KR, Sluijter JPG, van Steenbeek F, Steffens S, Terracciano CM, Tocchetti CG, Vlasman P, Yeung KK, Zacchigna S, Zwaagman D, Thum T. van der Velden J, et al. Among authors: bot i. Cardiovasc Res. 2022 Dec 9;118(15):3016-3051. doi: 10.1093/cvr/cvab370. Cardiovasc Res. 2022. PMID: 34999816 Free PMC article.
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.
Depuydt MAC, Prange KHM, Slenders L, Örd T, Elbersen D, Boltjes A, de Jager SCA, Asselbergs FW, de Borst GJ, Aavik E, Lönnberg T, Lutgens E, Glass CK, den Ruijter HM, Kaikkonen MU, Bot I, Slütter B, van der Laan SW, Yla-Herttuala S, Mokry M, Kuiper J, de Winther MPJ, Pasterkamp G. Depuydt MAC, et al. Among authors: bot i. Circ Res. 2020 Nov 6;127(11):1437-1455. doi: 10.1161/CIRCRESAHA.120.316770. Epub 2020 Sep 28. Circ Res. 2020. PMID: 32981416 Free PMC article.
Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis.
Segers FME, Ruder AV, Westra MM, Lammers T, Dadfar SM, Roemhild K, Lam TS, Kooi ME, Cleutjens KBJM, Verheyen FK, Schurink GWH, Haenen GR, van Berkel TJC, Bot I, Halvorsen B, Sluimer JC, Biessen EAL. Segers FME, et al. Among authors: bot i. Cardiovasc Res. 2023 Jan 18;118(17):3346-3359. doi: 10.1093/cvr/cvac032. Cardiovasc Res. 2023. PMID: 35325057 Free PMC article.
Single-cell profiling reveals age-associated immunity in atherosclerosis.
Smit V, de Mol J, Schaftenaar FH, Depuydt MAC, Postel RJ, Smeets D, Verheijen FWM, Bogers L, van Duijn J, Verwilligen RAF, Grievink HW, Bernabé Kleijn MNA, van Ingen E, de Jong MJM, Goncalves L, Peeters JAHM, Smeets HJ, Wezel A, Polansky JK, de Winther MPJ, Binder CJ, Tsiantoulas D, Bot I, Kuiper J, Foks AC. Smit V, et al. Among authors: bot i. Cardiovasc Res. 2023 Nov 25;119(15):2508-2521. doi: 10.1093/cvr/cvad099. Cardiovasc Res. 2023. PMID: 37390467 Free PMC article.
Anti-apoptotic serpins as therapeutics in cardiovascular diseases.
Kuiper J, Quax PH, Bot I. Kuiper J, et al. Among authors: bot i. Cardiovasc Hematol Disord Drug Targets. 2013 Aug;13(2):111-22. doi: 10.2174/1871529x11313020004. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 23987999 Review.
Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells.
Amersfoort J, Schaftenaar FH, Douna H, van Santbrink PJ, van Puijvelde GHM, Slütter B, Foks AC, Harms A, Moreno-Gordaliza E, Wang Y, Hankemeier T, Bot I, Chi H, Kuiper J. Amersfoort J, et al. Among authors: bot i. Cardiovasc Res. 2021 Apr 23;117(5):1309-1324. doi: 10.1093/cvr/cvaa208. Cardiovasc Res. 2021. PMID: 32653923 Free PMC article.
136 results