Bossard MJ - Search Results

1

PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs.

Turecek PL, Bossard MJ, Schoetens F, Ivens IA. Turecek PL, et al. Among authors: bossard mj. J Pharm Sci. 2016 Feb;105(2):460-475. doi: 10.1016/j.xphs.2015.11.015. J Pharm Sci. 2016. PMID: 26869412 Review.

2

Safety of PEGylated recombinant human full-length coagulation factor VIII (BAX 855) in the overall context of PEG and PEG conjugates.

Stidl R, Fuchs S, Bossard M, Siekmann J, Turecek PL, Putz M. Stidl R, et al. Haemophilia. 2016 Jan;22(1):54-64. doi: 10.1111/hae.12762. Epub 2015 Jul 29. Haemophilia. 2016. PMID: 26219204 Free PMC article.

3

BAX 855, a PEGylated rFVIII product with prolonged half-life. Development, functional and structural characterisation.

Turecek PL, Bossard MJ, Graninger M, Gritsch H, Höllriegl W, Kaliwoda M, Matthiessen P, Mitterer A, Muchitsch EM, Purtscher M, Rottensteiner H, Schiviz A, Schrenk G, Siekmann J, Varadi K, Riley T, Ehrlich HJ, Schwarz HP, Scheiflinger F. Turecek PL, et al. Among authors: bossard mj. Hamostaseologie. 2012;32 Suppl 1:S29-38. Hamostaseologie. 2012. PMID: 22961422

4

Microchip capillary gel electrophoresis of multiply PEGylated high-molecular-mass glycoproteins.

Seyfried BK, Marchetti-Deschmann M, Siekmann J, Bossard MJ, Scheiflinger F, Turecek PL, Allmaier G. Seyfried BK, et al. Among authors: bossard mj. Biotechnol J. 2012 May;7(5):635-41. doi: 10.1002/biot.201100407. Biotechnol J. 2012. PMID: 22407778

5

PEGylation of cyanovirin-N, an entry inhibitor of HIV.

Zappe H, Snell ME, Bossard MJ. Zappe H, et al. Among authors: bossard mj. Adv Drug Deliv Rev. 2008 Jan 3;60(1):79-87. doi: 10.1016/j.addr.2007.05.016. Epub 2007 Aug 16. Adv Drug Deliv Rev. 2008. PMID: 17884238 Review.

6

Mechanism of inhibition of cathepsin K by potent, selective 1, 5-diacylcarbohydrazides: a new class of mechanism-based inhibitors of thiol proteases.

Bossard MJ, Tomaszek TA, Levy MA, Ijames CF, Huddleston MJ, Briand J, Thompson S, Halpert S, Veber DF, Carr SA, Meek TD, Tew DG. Bossard MJ, et al. Biochemistry. 1999 Nov 30;38(48):15893-902. doi: 10.1021/bi991193+. Biochemistry. 1999. PMID: 10625455

7

Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K.

Duffy KJ, Ridgers LH, DesJarlais RL, Tomaszek TA, Bossard MJ, Thompson SK, Keenan RM, Veber DF. Duffy KJ, et al. Among authors: bossard mj. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1907-10. doi: 10.1016/s0960-894x(99)00322-4. Bioorg Med Chem Lett. 1999. PMID: 10450951

8

Design of potent and selective human cathepsin K inhibitors that span the active site.

Thompson SK, Halbert SM, Bossard MJ, Tomaszek TA, Levy MA, Zhao B, Smith WW, Abdel-Meguid SS, Janson CA, D'Alessio KJ, McQueney MS, Amegadzie BY, Hanning CR, DesJarlais RL, Briand J, Sarkar SK, Huddleston MJ, Ijames CF, Carr SA, Garnes KT, Shu A, Heys JR, Bradbeer J, Zembryki D, Lee-Rykaczewski L, James IE, Lark MW, Drake FH, Gowen M, Gleason JG, Veber DF. Thompson SK, et al. Among authors: bossard mj. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14249-54. doi: 10.1073/pnas.94.26.14249. Proc Natl Acad Sci U S A. 1997. PMID: 9405598 Free PMC article.

9

Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo.

Votta BJ, Levy MA, Badger A, Bradbeer J, Dodds RA, James IE, Thompson S, Bossard MJ, Carr T, Connor JR, Tomaszek TA, Szewczuk L, Drake FH, Veber DF, Gowen M. Votta BJ, et al. Among authors: bossard mj. J Bone Miner Res. 1997 Sep;12(9):1396-406. doi: 10.1359/jbmr.1997.12.9.1396. J Bone Miner Res. 1997. PMID: 9286755 Free article.

10

Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification.

Bossard MJ, Tomaszek TA, Thompson SK, Amegadzie BY, Hanning CR, Jones C, Kurdyla JT, McNulty DE, Drake FH, Gowen M, Levy MA. Bossard MJ, et al. J Biol Chem. 1996 May 24;271(21):12517-24. doi: 10.1074/jbc.271.21.12517. J Biol Chem. 1996. PMID: 8647860 Free article.

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