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In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV.
Montenegro-Miranda PS, Pichard V, Aubert D, Ten Bloemendaal L, Duijst S, de Waart DR, Ferry N, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: bosma pj. Gene Ther. 2014 Feb;21(2):168-74. doi: 10.1038/gt.2013.69. Epub 2013 Nov 28. Gene Ther. 2014. PMID: 24285217
Adeno-associated viral vector serotype 5 poorly transduces liver in rat models.
Montenegro-Miranda PS, Pañeda A, ten Bloemendaal L, Duijst S, de Waart DR, Gonzalez- Aseguinolaza G, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: bosma pj. PLoS One. 2013 Dec 27;8(12):e82597. doi: 10.1371/journal.pone.0082597. eCollection 2013. PLoS One. 2013. PMID: 24386104 Free PMC article.
A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome.
Ronzitti G, Bortolussi G, van Dijk R, Collaud F, Charles S, Leborgne C, Vidal P, Martin S, Gjata B, Sola MS, van Wittenberghe L, Vignaud A, Veron P, Bosma PJ, Muro AF, Mingozzi F. Ronzitti G, et al. Among authors: bosma pj. Mol Ther Methods Clin Dev. 2016 Jul 20;3:16049. doi: 10.1038/mtm.2016.49. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27722180 Free PMC article.
Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome.
Collaud F, Bortolussi G, Guianvarc'h L, Aronson SJ, Bordet T, Veron P, Charles S, Vidal P, Sola MS, Rundwasser S, Dufour DG, Lacoste F, Luc C, Wittenberghe LV, Martin S, Le Bec C, Bosma PJ, Muro AF, Ronzitti G, Hebben M, Mingozzi F. Collaud F, et al. Among authors: bosma pj. Mol Ther Methods Clin Dev. 2018 Dec 31;12:157-174. doi: 10.1016/j.omtm.2018.12.011. eCollection 2019 Mar 15. Mol Ther Methods Clin Dev. 2018. PMID: 30705921 Free PMC article.
The P4-ATPase ATP9A is a novel determinant of exosome release.
Naik J, Hau CM, Ten Bloemendaal L, Mok KS, Hajji N, Wehman AM, Meisner S, Muncan V, Paauw NJ, de Vries HE, Nieuwland R, Paulusma CC, Bosma PJ. Naik J, et al. Among authors: bosma pj. PLoS One. 2019 Apr 4;14(4):e0213069. doi: 10.1371/journal.pone.0213069. eCollection 2019. PLoS One. 2019. PMID: 30947313 Free PMC article.
96 results