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Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion.
Joas S, Sauermann U, Roshani B, Klippert A, Daskalaki M, Mätz-Rensing K, Stolte-Leeb N, Heigele A, Tharp GK, Gupta PM, Nelson S, Bosinger S, Parodi L, Giavedoni L, Silvestri G, Sauter D, Stahl-Hennig C, Kirchhoff F. Joas S, et al. Among authors: bosinger s. Cell Rep. 2020 Feb 18;30(7):2261-2274.e7. doi: 10.1016/j.celrep.2020.01.069. Cell Rep. 2020. PMID: 32075764 Free PMC article.
CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection.
Vanderheiden A, Thomas J, Soung AL, Davis-Gardner ME, Floyd K, Jin F, Cowan DA, Pellegrini K, Creanga A, Pegu A, Derrien-Colemyn A, Shi PY, Grakoui A, Klein RS, Bosinger SE, Kohlmeier JE, Menachery VD, Suthar MS. Vanderheiden A, et al. Among authors: bosinger se. bioRxiv [Preprint]. 2021 May 4:2021.05.03.442538. doi: 10.1101/2021.05.03.442538. bioRxiv. 2021. PMID: 33972938 Free PMC article. Updated. Preprint.
Copper intrauterine device increases vaginal concentrations of inflammatory anaerobes and depletes lactobacilli compared to hormonal options in a randomized trial.
Brown BP, Feng C, Tanko RF, Jaumdally SZ, Bunjun R, Dabee S, Happel AU, Gasper M, Nyangahu DD, Onono M, Nair G, Palanee-Phillips T, Scoville CW, Heller K, Baeten JM, Bosinger SE, Burgener A, Passmore JS, Heffron R, Jaspan HB. Brown BP, et al. Among authors: bosinger se. Nat Commun. 2023 Jan 30;14(1):499. doi: 10.1038/s41467-023-36002-4. Nat Commun. 2023. PMID: 36717556 Free PMC article. Clinical Trial.
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.
Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush JM, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, Staprans SI, Sodora DL, Silvestri G. Gordon SN, et al. Among authors: bosinger se. J Immunol. 2007 Sep 1;179(5):3026-34. doi: 10.4049/jimmunol.179.5.3026. J Immunol. 2007. PMID: 17709517 Free PMC article.
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys.
Bosinger SE, Li Q, Gordon SN, Klatt NR, Duan L, Xu L, Francella N, Sidahmed A, Smith AJ, Cramer EM, Zeng M, Masopust D, Carlis JV, Ran L, Vanderford TH, Paiardini M, Isett RB, Baldwin DA, Else JG, Staprans SI, Silvestri G, Haase AT, Kelvin DJ. Bosinger SE, et al. J Clin Invest. 2009 Dec;119(12):3556-72. doi: 10.1172/JCI40115. J Clin Invest. 2009. PMID: 19959874 Free PMC article.
Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression.
Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, Vinton C, Gordon SN, Bosinger SE, Francella N, Hallberg PL, Cramer E, Schlub T, Chan ML, Riddick NE, Collman RG, Apetrei C, Pandrea I, Else J, Munch J, Kirchhoff F, Davenport MP, Brenchley JM, Silvestri G. Paiardini M, et al. Nat Med. 2011 Jun 26;17(7):830-6. doi: 10.1038/nm.2395. Nat Med. 2011. PMID: 21706028 Free PMC article.
Primate genomes for biomedicine.
Bosinger SE, Johnson ZP, Silvestri G. Bosinger SE, et al. Nat Biotechnol. 2011 Nov 8;29(11):983-4. doi: 10.1038/nbt.2032. Nat Biotechnol. 2011. PMID: 22068533 Free PMC article.
162 results