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A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission.
Bachmaier S, Giacomelli G, Calvo-Alvarez E, Vieira LR, Van Den Abbeele J, Aristodemou A, Lorentzen E, Gould MK, Brennand A, Dupuy JW, Forné I, Imhof A, Bramkamp M, Salmon D, Rotureau B, Boshart M. Bachmaier S, et al. Among authors: boshart m. Nat Commun. 2022 Sep 16;13(1):5445. doi: 10.1038/s41467-022-33108-z. Nat Commun. 2022. PMID: 36114198 Free PMC article.
Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host.
Salmon D, Vanwalleghem G, Morias Y, Denoeud J, Krumbholz C, Lhommé F, Bachmaier S, Kador M, Gossmann J, Dias FB, De Muylder G, Uzureau P, Magez S, Moser M, De Baetselier P, Van Den Abbeele J, Beschin A, Boshart M, Pays E. Salmon D, et al. Among authors: boshart m. Science. 2012 Jul 27;337(6093):463-6. doi: 10.1126/science.1222753. Epub 2012 Jun 14. Science. 2012. PMID: 22700656
Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.
Allmann S, Morand P, Ebikeme C, Gales L, Biran M, Hubert J, Brennand A, Mazet M, Franconi JM, Michels PA, Portais JC, Boshart M, Bringaud F. Allmann S, et al. Among authors: boshart m. J Biol Chem. 2013 Jun 21;288(25):18494-505. doi: 10.1074/jbc.M113.462978. Epub 2013 May 10. J Biol Chem. 2013. PMID: 23665470 Free PMC article.
Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA.
Gould MK, Bachmaier S, Ali JA, Alsford S, Tagoe DN, Munday JC, Schnaufer AC, Horn D, Boshart M, de Koning HP. Gould MK, et al. Among authors: boshart m. Antimicrob Agents Chemother. 2013 Oct;57(10):4882-93. doi: 10.1128/AAC.00508-13. Epub 2013 Jul 22. Antimicrob Agents Chemother. 2013. PMID: 23877697 Free PMC article.
Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei.
Allmann S, Mazet M, Ziebart N, Bouyssou G, Fouillen L, Dupuy JW, Bonneu M, Moreau P, Bringaud F, Boshart M. Allmann S, et al. Among authors: boshart m. PLoS One. 2014 Dec 10;9(12):e114628. doi: 10.1371/journal.pone.0114628. eCollection 2014. PLoS One. 2014. PMID: 25493940 Free PMC article.
Gluconeogenesis is essential for trypanosome development in the tsetse fly vector.
Wargnies M, Bertiaux E, Cahoreau E, Ziebart N, Crouzols A, Morand P, Biran M, Allmann S, Hubert J, Villafraz O, Millerioux Y, Plazolles N, Asencio C, Rivière L, Rotureau B, Boshart M, Portais JC, Bringaud F. Wargnies M, et al. Among authors: boshart m. PLoS Pathog. 2018 Dec 17;14(12):e1007502. doi: 10.1371/journal.ppat.1007502. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30557412 Free PMC article.
Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.
Bachmaier S, Volpato Santos Y, Kramer S, Githure GB, Klöckner T, Pepperl J, Baums C, Schenk R, Schwede F, Genieser HG, Dupuy JW, Forné I, Imhof A, Basquin J, Lorentzen E, Boshart M. Bachmaier S, et al. Among authors: boshart m. Nat Commun. 2019 Mar 29;10(1):1421. doi: 10.1038/s41467-019-09338-z. Nat Commun. 2019. PMID: 30926779 Free PMC article.
A unified multi-kingdom Golden Gate cloning platform.
Chiasson D, Giménez-Oya V, Bircheneder M, Bachmaier S, Studtrucker T, Ryan J, Sollweck K, Leonhardt H, Boshart M, Dietrich P, Parniske M. Chiasson D, et al. Among authors: boshart m. Sci Rep. 2019 Jul 12;9(1):10131. doi: 10.1038/s41598-019-46171-2. Sci Rep. 2019. PMID: 31300661 Free PMC article.
81 results