Bose A - Search Results

1

Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers.

Patterson-Fortin J, Bose A, Tsai WC, Grochala C, Nguyen H, Zhou J, Parmar K, Lazaro JB, Liu J, McQueen K, Shapiro GI, Kozono D, D'Andrea AD. Patterson-Fortin J, et al. Among authors: bose a. Cancer Res. 2022 Oct 17;82(20):3815-3829. doi: 10.1158/0008-5472.CAN-22-1124. Cancer Res. 2022. PMID: 35972384 Free PMC article.

2

PDX-derived organoids model in vivo drug response and secrete biomarkers.

Huang L, Bockorny B, Paul I, Akshinthala D, Frappart PO, Gandarilla O, Bose A, Sanchez-Gonzalez V, Rouse EE, Lehoux SD, Pandell N, Lim CM, Clohessy JG, Grossman J, Gonzalez R, Del Pino SP, Daaboul G, Sawhney MS, Freedman SD, Kleger A, Cummings RD, Emili A, Muthuswamy LB, Hidalgo M, Muthuswamy SK. Huang L, et al. Among authors: bose a. JCI Insight. 2020 Nov 5;5(21):e135544. doi: 10.1172/jci.insight.135544. JCI Insight. 2020. PMID: 32990680 Free PMC article.

3

Elevated levels of mitochondrial CoQ₁₀ induce ROS-mediated apoptosis in pancreatic cancer.

Dadali T, Diers AR, Kazerounian S, Muthuswamy SK, Awate P, Ng R, Mogre S, Spencer C, Krumova K, Rockwell HE, McDaniel J, Chen EY, Gao F, Diedrich KT, Vemulapalli V, Rodrigues LO, Akmaev VR, Thapa K, Hidalgo M, Bose A, Vishnudas VK, Moser AJ, Granger E, Kiebish MA, Gesta S, Narain NR, Sarangarajan R. Dadali T, et al. Among authors: bose a. Sci Rep. 2021 Mar 11;11(1):5749. doi: 10.1038/s41598-021-84852-z. Sci Rep. 2021. PMID: 33707480 Free PMC article.

4

Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.

Basu AK, Pande P, Bose A. Basu AK, et al. Among authors: bose a. Chem Res Toxicol. 2017 Jan 17;30(1):61-72. doi: 10.1021/acs.chemrestox.6b00285. Epub 2016 Nov 1. Chem Res Toxicol. 2017. PMID: 27760288 Free PMC article.

5

Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.

Pande P, Malik CK, Bose A, Jasti VP, Basu AK. Pande P, et al. Among authors: bose a. Biochemistry. 2014 Aug 19;53(32):5323-31. doi: 10.1021/bi5007805. Epub 2014 Aug 6. Biochemistry. 2014. PMID: 25080294 Free PMC article.

6

DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.

Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK. Bose A, et al. Nucleic Acids Res. 2015 Sep 30;43(17):8340-51. doi: 10.1093/nar/gkv750. Epub 2015 Jul 28. Nucleic Acids Res. 2015. PMID: 26220181 Free PMC article.

7

Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O2-alkylthymidines in human cells.

Weerasooriya S, Jasti VP, Bose A, Spratt TE, Basu AK. Weerasooriya S, et al. Among authors: bose a. DNA Repair (Amst). 2015 Nov;35:63-70. doi: 10.1016/j.dnarep.2015.09.023. Epub 2015 Sep 21. DNA Repair (Amst). 2015. PMID: 26460881 Free PMC article.

8

Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxyguanosine Adducts Formed by Mitomycin C and Its Metabolite, 2,7-Diaminomitosene, in Human Cells.

Bose A, Surugihalli C, Pande P, Champeil E, Basu AK. Bose A, et al. Chem Res Toxicol. 2016 May 16;29(5):933-9. doi: 10.1021/acs.chemrestox.6b00087. Epub 2016 Apr 27. Chem Res Toxicol. 2016. PMID: 27082015 Free PMC article.

9

Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1.

Bose A, Millsap AD, DeLeon A, Rizzo CJ, Basu AK. Bose A, et al. Chem Res Toxicol. 2016 Sep 19;29(9):1549-59. doi: 10.1021/acs.chemrestox.6b00221. Epub 2016 Aug 17. Chem Res Toxicol. 2016. PMID: 27490094 Free PMC article.

10

Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres.

Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ. Garcia-Exposito L, et al. Among authors: bose a. Cell Rep. 2016 Nov 8;17(7):1858-1871. doi: 10.1016/j.celrep.2016.10.048. Cell Rep. 2016. PMID: 27829156 Free PMC article.

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