Borysko P - Search Results

1

Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces.

Müller J, Klein R, Tarkhanova O, Gryniukova A, Borysko P, Merkl S, Ruf M, Neumann A, Gastreich M, Moroz YS, Klebe G, Glinca S. Müller J, et al. Among authors: borysko p. J Med Chem. 2022 Dec 8;65(23):15663-15678. doi: 10.1021/acs.jmedchem.2c00813. Epub 2022 Sep 7. J Med Chem. 2022. PMID: 36069712

2

Straightforward hit identification approach in fragment-based discovery of bromodomain-containing protein 4 (BRD4) inhibitors.

Borysko P, Moroz YS, Vasylchenko OV, Hurmach VV, Starodubtseva A, Stefanishena N, Nesteruk K, Zozulya S, Kondratov IS, Grygorenko OO. Borysko P, et al. Bioorg Med Chem. 2018 Jul 23;26(12):3399-3405. doi: 10.1016/j.bmc.2018.05.010. Epub 2018 May 9. Bioorg Med Chem. 2018. PMID: 29764756

3

(Chlorosulfonyl)benzenesulfonyl Fluorides-Versatile Building Blocks for Combinatorial Chemistry: Design, Synthesis and Evaluation of a Covalent Inhibitor Library.

Tolmachova KA, Moroz YS, Konovets A, Platonov MO, Vasylchenko OV, Borysko P, Zozulya S, Gryniukova A, Bogolubsky AV, Pipko S, Mykhailiuk PK, Brovarets VS, Grygorenko OO. Tolmachova KA, et al. Among authors: borysko p. ACS Comb Sci. 2018 Nov 12;20(11):672-680. doi: 10.1021/acscombsci.8b00130. Epub 2018 Nov 1. ACS Comb Sci. 2018. PMID: 30354064

4

Pros and cons of virtual screening based on public "Big Data": In silico mining for new bromodomain inhibitors.

Casciuc I, Horvath D, Gryniukova A, Tolmachova KA, Vasylchenko OV, Borysko P, Moroz YS, Bajorath J, Varnek A. Casciuc I, et al. Among authors: borysko p. Eur J Med Chem. 2019 Mar 1;165:258-272. doi: 10.1016/j.ejmech.2019.01.010. Epub 2019 Jan 9. Eur J Med Chem. 2019. PMID: 30685526

5

SAR by Space: Enriching Hit Sets from the Chemical Space.

Klingler FM, Gastreich M, Grygorenko OO, Savych O, Borysko P, Griniukova A, Gubina KE, Lemmen C, Moroz YS. Klingler FM, et al. Among authors: borysko p. Molecules. 2019 Aug 26;24(17):3096. doi: 10.3390/molecules24173096. Molecules. 2019. PMID: 31454992 Free PMC article.

6

Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry.

Krasavin M, Kalinin S, Zozulya S, Gryniukova A, Borysko P, Angeli A, Supuran CT. Krasavin M, et al. Among authors: borysko p. J Enzyme Inhib Med Chem. 2020 Dec;35(1):306-310. doi: 10.1080/14756366.2019.1698562. J Enzyme Inhib Med Chem. 2020. PMID: 31797704 Free PMC article.

7

AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1.

Gryniukova A, Kaiser F, Myziuk I, Alieksieieva D, Leberecht C, Heym PP, Tarkhanova OO, Moroz YS, Borysko P, Haupt VJ. Gryniukova A, et al. Among authors: borysko p. J Med Chem. 2023 Aug 10;66(15):10241-10251. doi: 10.1021/acs.jmedchem.3c00128. Epub 2023 Jul 27. J Med Chem. 2023. PMID: 37499195

8

Anticancer activity features of imidazole-based ionic liquids and lysosomotropic detergents: in silico and in vitro studies.

Gryniukova A, Borysko P, Myziuk I, Alieksieieva D, Hodyna D, Semenyuta I, Kovalishyn V, Metelytsia L, Rogalsky S, Tcherniuk S. Gryniukova A, et al. Among authors: borysko p. Mol Divers. 2024 Jan 22. doi: 10.1007/s11030-023-10779-4. Online ahead of print. Mol Divers. 2024. PMID: 38246950

9

Novel 5,7-disubstituted 6-amino-5H-pyrrolo[3,2-b]pyrazine-2,3-dicarbonitriles, the promising protein kinase inhibitors with antiproliferative activity.

Dubinina GG, Platonov MO, Golovach SM, Borysko PO, Tolmachov AO, Volovenko YM. Dubinina GG, et al. Among authors: borysko po. Eur J Med Chem. 2006 Jun;41(6):727-37. doi: 10.1016/j.ejmech.2006.03.019. Epub 2006 May 3. Eur J Med Chem. 2006. PMID: 16675067

10

Continued SAR exploration of 1,2,4-thiadiazole-containing scaffolds in the design of free fatty acid receptor 1 (GPR40) agonists.

Krasavin M, Lukin A, Bakholdina A, Zhurilo N, Onopchenko O, Borysko P, Zozulya S, Moore D, Tikhonova IG. Krasavin M, et al. Among authors: borysko p. Eur J Med Chem. 2017 Nov 10;140:229-238. doi: 10.1016/j.ejmech.2017.09.019. Epub 2017 Sep 13. Eur J Med Chem. 2017. PMID: 28938138

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

31 results

Search Page