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Molecular architecture of the autoinhibited kinesin-1 lambda particle.
Weijman JF, Yadav SKN, Surridge KJ, Cross JA, Borucu U, Mantell J, Woolfson DN, Schaffitzel C, Dodding MP. Weijman JF, et al. Among authors: borucu u. Sci Adv. 2022 Sep 16;8(37):eabp9660. doi: 10.1126/sciadv.abp9660. Epub 2022 Sep 16. Sci Adv. 2022. PMID: 36112680 Free PMC article.
Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.
Toelzer C, Gupta K, Yadav SKN, Borucu U, Davidson AD, Kavanagh Williamson M, Shoemark DK, Garzoni F, Staufer O, Milligan R, Capin J, Mulholland AJ, Spatz J, Fitzgerald D, Berger I, Schaffitzel C. Toelzer C, et al. Among authors: borucu u. Science. 2020 Nov 6;370(6517):725-730. doi: 10.1126/science.abd3255. Epub 2020 Sep 21. Science. 2020. PMID: 32958580 Free PMC article.
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Gupta K, Toelzer C, Williamson MK, Shoemark DK, Oliveira ASF, Matthews DA, Almuqrin A, Staufer O, Yadav SKN, Borucu U, Garzoni F, Fitzgerald D, Spatz J, Mulholland AJ, Davidson AD, Schaffitzel C, Berger I. Gupta K, et al. Among authors: borucu u. Nat Commun. 2022 Jan 11;13(1):222. doi: 10.1038/s41467-021-27881-6. Nat Commun. 2022. PMID: 35017512 Free PMC article.
The free fatty acid-binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron.
Toelzer C, Gupta K, Yadav SKN, Hodgson L, Williamson MK, Buzas D, Borucu U, Powers K, Stenner R, Vasileiou K, Garzoni F, Fitzgerald D, Payré C, Gautam G, Lambeau G, Davidson AD, Verkade P, Frank M, Berger I, Schaffitzel C. Toelzer C, et al. Among authors: borucu u. Sci Adv. 2022 Nov 25;8(47):eadc9179. doi: 10.1126/sciadv.adc9179. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417532 Free PMC article.
Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Healy MD, McNally KE, Butkovič R, Chilton M, Kato K, Sacharz J, McConville C, Moody ERR, Shaw S, Planelles-Herrero VJ, Yadav SKN, Ross J, Borucu U, Palmer CS, Chen KE, Croll TI, Hall RJ, Caruana NJ, Ghai R, Nguyen THD, Heesom KJ, Saitoh S, Berger I, Schaffitzel C, Williams TA, Stroud DA, Derivery E, Collins BM, Cullen PJ. Healy MD, et al. Among authors: borucu u. Cell. 2023 May 11;186(10):2219-2237.e29. doi: 10.1016/j.cell.2023.04.003. Cell. 2023. PMID: 37172566 Free PMC article.
In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2.
Buzas D, Bunzel AH, Staufer O, Milodowski EJ, Edmunds GL, Bufton JC, Vidana Mateo BV, Yadav SKN, Gupta K, Fletcher C, Williamson MK, Harrison A, Borucu U, Capin J, Francis O, Balchin G, Hall S, Vega MV, Durbesson F, Lingappa S, Vincentelli R, Roe J, Wooldridge L, Burt R, Anderson RJL, Mulholland AJ, Bristol Uncover Group, Hare J, Bailey M, Davidson AD, Finn A, Morgan D, Mann J, Spatz J, Garzoni F, Schaffitzel C, Berger I. Buzas D, et al. Among authors: borucu u. Antib Ther. 2023 Oct 17;6(4):277-297. doi: 10.1093/abt/tbad024. eCollection 2023 Oct. Antib Ther. 2023. PMID: 38075238 Free PMC article.
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