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ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.
Augustyn A, Borromeo M, Wang T, Fujimoto J, Shao C, Dospoy PD, Lee V, Tan C, Sullivan JP, Larsen JE, Girard L, Behrens C, Wistuba II, Xie Y, Cobb MH, Gazdar AF, Johnson JE, Minna JD. Augustyn A, et al. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14788-93. doi: 10.1073/pnas.1410419111. Epub 2014 Sep 29. Proc Natl Acad Sci U S A. 2014. PMID: 25267614 Free PMC article.
Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility.
Meredith DM, Borromeo MD, Deering TG, Casey BH, Savage TK, Mayer PR, Hoang C, Tung KC, Kumar M, Shen C, Swift GH, Macdonald RJ, Johnson JE. Meredith DM, et al. Among authors: borromeo md. Mol Cell Biol. 2013 Aug;33(16):3166-79. doi: 10.1128/MCB.00364-13. Epub 2013 Jun 10. Mol Cell Biol. 2013. PMID: 23754747 Free PMC article.
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