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Mechanism-Based Design of Efficient PET Hydrolases.
Wei R, von Haugwitz G, Pfaff L, Mican J, Badenhorst CPS, Liu W, Weber G, Austin HP, Bednar D, Damborsky J, Bornscheuer UT. Wei R, et al. Among authors: bornscheuer ut. ACS Catal. 2022 Mar 18;12(6):3382-3396. doi: 10.1021/acscatal.1c05856. Epub 2022 Feb 28. ACS Catal. 2022. PMID: 35368328 Free PMC article. Review.
Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
Koudelakova T, Chaloupkova R, Brezovsky J, Prokop Z, Sebestova E, Hesseler M, Khabiri M, Plevaka M, Kulik D, Kuta Smatanova I, Rezacova P, Ettrich R, Bornscheuer UT, Damborsky J. Koudelakova T, et al. Among authors: bornscheuer ut. Angew Chem Int Ed Engl. 2013 Feb 11;52(7):1959-63. doi: 10.1002/anie.201206708. Epub 2013 Jan 9. Angew Chem Int Ed Engl. 2013. PMID: 23303607 No abstract available.
NewProt - a protein engineering portal.
Schwarte A, Genz M, Skalden L, Nobili A, Vickers C, Melse O, Kuipers R, Joosten HJ, Stourac J, Bendl J, Black J, Haase P, Baakman C, Damborsky J, Bornscheuer U, Vriend G, Venselaar H. Schwarte A, et al. Protein Eng Des Sel. 2017 Jun 1;30(6):441-447. doi: 10.1093/protein/gzx024. Protein Eng Des Sel. 2017. PMID: 28475759
Sequence-Based Prediction of Promiscuous Acyltransferase Activity in Hydrolases.
Müller H, Becker AK, Palm GJ, Berndt L, Badenhorst CPS, Godehard SP, Reisky L, Lammers M, Bornscheuer UT. Müller H, et al. Among authors: bornscheuer ut. Angew Chem Int Ed Engl. 2020 Jul 6;59(28):11607-11612. doi: 10.1002/anie.202003635. Epub 2020 May 11. Angew Chem Int Ed Engl. 2020. PMID: 32243661 Free PMC article.
An Ultrasensitive Fluorescence Assay for the Detection of Halides and Enzymatic Dehalogenation.
Aslan-Üzel AS, Beier A, Kovář D, Cziegler C, Padhi SK, Schuiten ED, Dörr M, Böttcher D, Hollmann F, Rudroff F, Mihovilovic MD, Buryška T, Damborský J, Prokop Z, Badenhorst CPS, Bornscheuer UT. Aslan-Üzel AS, et al. Among authors: bornscheuer ut. ChemCatChem. 2020 Apr 6;12(7):2032-2039. doi: 10.1002/cctc.201901891. Epub 2020 Jan 31. ChemCatChem. 2020. PMID: 32362951 Free PMC article.
Engineering Regioselectivity of a P450 Monooxygenase Enables the Synthesis of Ursodeoxycholic Acid via 7β-Hydroxylation of Lithocholic Acid.
Grobe S, Badenhorst CPS, Bayer T, Hamnevik E, Wu S, Grathwol CW, Link A, Koban S, Brundiek H, Großjohann B, Bornscheuer UT. Grobe S, et al. Among authors: bornscheuer ut. Angew Chem Int Ed Engl. 2021 Jan 11;60(2):753-757. doi: 10.1002/anie.202012675. Epub 2020 Nov 12. Angew Chem Int Ed Engl. 2021. PMID: 33085147 Free PMC article.
329 results